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Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming.
Schiebinger G, Shu J, Tabaka M, Cleary B, Subramanian V, Solomon A, Gould J, Liu S, Lin S, Berube P, Lee L, Chen J, Brumbaugh J, Rigollet P, Hochedlinger K, Jaenisch R, Regev A, Lander ES. Schiebinger G, et al. Among authors: brumbaugh j. Cell. 2019 Mar 7;176(6):1517. doi: 10.1016/j.cell.2019.02.026. Cell. 2019. PMID: 30849376 Free PMC article. No abstract available.
Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming.
Schiebinger G, Shu J, Tabaka M, Cleary B, Subramanian V, Solomon A, Gould J, Liu S, Lin S, Berube P, Lee L, Chen J, Brumbaugh J, Rigollet P, Hochedlinger K, Jaenisch R, Regev A, Lander ES. Schiebinger G, et al. Among authors: brumbaugh j. Cell. 2019 Feb 7;176(4):928-943.e22. doi: 10.1016/j.cell.2019.01.006. Epub 2019 Jan 31. Cell. 2019. PMID: 30712874 Free PMC article.
A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.
Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K. Borkent M, et al. Among authors: brumbaugh j. Stem Cell Reports. 2016 May 10;6(5):704-716. doi: 10.1016/j.stemcr.2016.02.004. Epub 2016 Mar 3. Stem Cell Reports. 2016. PMID: 26947976 Free PMC article.
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T. Sardina JL, et al. Among authors: brumbaugh j. Cell Stem Cell. 2018 Dec 6;23(6):905-906. doi: 10.1016/j.stem.2018.11.001. Cell Stem Cell. 2018. PMID: 30526885 Free PMC article. No abstract available.
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K. Brumbaugh J, et al. Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28. Nat Cell Biol. 2019. PMID: 31659274 Free PMC article.
Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K. Brumbaugh J, et al. Cell. 2018 Jan 11;172(1-2):106-120.e21. doi: 10.1016/j.cell.2017.11.023. Epub 2017 Dec 14. Cell. 2018. PMID: 29249356 Free PMC article.
182 results