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Cytoskeletal actin patterns shape mast cell activation.
Colin-York H, Li D, Korobchevskaya K, Chang VT, Betzig E, Eggeling C, Fritzsche M. Colin-York H, et al. Among authors: chang vt. Commun Biol. 2019 Mar 7;2:93. doi: 10.1038/s42003-019-0322-9. eCollection 2019. Commun Biol. 2019. PMID: 30854485 Free PMC article.
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.
Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM, Pedroza-Pacheco I, Waithe D, de la Serna JB, Lagerholm BC, Liu TL, Chew TL, Betzig E, Davis SJ, Eggeling C. Fritzsche M, et al. Among authors: chang vt. Sci Adv. 2017 Jun 21;3(6):e1603032. doi: 10.1126/sciadv.1603032. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28691087 Free PMC article.
Cytoskeletal Control of Antigen-Dependent T Cell Activation.
Colin-York H, Javanmardi Y, Skamrahl M, Kumari S, Chang VT, Khuon S, Taylor A, Chew TL, Betzig E, Moeendarbary E, Cerundolo V, Eggeling C, Fritzsche M. Colin-York H, et al. Among authors: chang vt. Cell Rep. 2019 Mar 19;26(12):3369-3379.e5. doi: 10.1016/j.celrep.2019.02.074. Cell Rep. 2019. PMID: 30893608 Free PMC article.
Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.
Yu C, Crispin M, Sonnen AF, Harvey DJ, Chang VT, Evans EJ, Scanlan CN, Stuart DI, Gilbert RJ, Davis SJ. Yu C, et al. Among authors: chang vt. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jul 1;67(Pt 7):785-9. doi: 10.1107/S1744309111017672. Epub 2011 Jun 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21795794 Free PMC article.
A cell topography-based mechanism for ligand discrimination by the T cell receptor.
Fernandes RA, Ganzinger KA, Tzou JC, Jönsson P, Lee SF, Palayret M, Santos AM, Carr AR, Ponjavic A, Chang VT, Macleod C, Lagerholm BC, Lindsay AE, Dushek O, Tilevik A, Davis SJ, Klenerman D. Fernandes RA, et al. Among authors: chang vt. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14002-14010. doi: 10.1073/pnas.1817255116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221762 Free PMC article.
Initiation of T cell signaling by CD45 segregation at 'close contacts'.
Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJC, Klenerman D, Aricescu AR, Davis SJ. Chang VT, et al. Nat Immunol. 2016 May;17(5):574-582. doi: 10.1038/ni.3392. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998761 Free PMC article.
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Gaynor KU, Vaysburd M, Harman MAJ, Albecka A, Jeffrey P, Beswick P, Papa G, Chen L, Mallery D, McGuinness B, Van Rietschoten K, Stanway S, Brear P, Lulla A, Ciazynska K, Chang VT, Sharp J, Neary M, Box H, Herriott J, Kijak E, Tatham L, Bentley EG, Sharma P, Kirby A, Han X, Stewart JP, Owen A, Briggs JAG, Hyvönen M, Skynner MJ, James LC. Gaynor KU, et al. Among authors: chang vt. Nat Commun. 2023 Jun 16;14(1):3583. doi: 10.1038/s41467-023-39158-1. Nat Commun. 2023. PMID: 37328472 Free PMC article.
130 results