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Dopamine D4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy.
Keck TM, Free RB, Day MM, Brown SL, Maddaluna MS, Fountain G, Cooper C, Fallon B, Holmes M, Stang CT, Burkhardt R, Bonifazi A, Ellenberger MP, Newman AH, Sibley DR, Wu C, Boateng CA. Keck TM, et al. Among authors: burkhardt r. J Med Chem. 2019 Apr 11;62(7):3722-3740. doi: 10.1021/acs.jmedchem.9b00231. Epub 2019 Apr 1. J Med Chem. 2019. PMID: 30883109 Free PMC article.
An excreted small molecule promotes C. elegans reproductive development and aging.
Ludewig AH, Artyukhin AB, Aprison EZ, Rodrigues PR, Pulido DC, Burkhardt RN, Panda O, Zhang YK, Gudibanda P, Ruvinsky I, Schroeder FC. Ludewig AH, et al. Among authors: burkhardt rn. Nat Chem Biol. 2019 Aug;15(8):838-845. doi: 10.1038/s41589-019-0321-7. Epub 2019 Jul 18. Nat Chem Biol. 2019. PMID: 31320757 Free PMC article.
Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice.
Potì F, Scalera E, Feuerborn R, Fischer J, Arndt L, Varga G, Pardali E, Seidl MD, Fobker M, Liebisch G, Hesse B, Lukasz AH, Rossaint J, Kehrel BE, Rosenbauer F, Renné T, Christoffersen C, Simoni M, Burkhardt R, Nofer JR. Potì F, et al. Among authors: burkhardt r. JCI Insight. 2024 Dec 20;9(24):e158127. doi: 10.1172/jci.insight.158127. JCI Insight. 2024. PMID: 39531328 Free PMC article.
Therapeutic and pharmacological applications of extracellular vesicles and lipoproteins.
Németh K, Kestecher BM, Ghosal S, Bodnár BR, Kittel Á, Hambalkó S, Kovácsházi C, Giricz Z, Ferdinandy P, Osteikoetxea X, Burkhardt R, Buzas EI, Orsó E. Németh K, et al. Among authors: burkhardt r. Br J Pharmacol. 2024 Dec;181(23):4733-4749. doi: 10.1111/bph.17336. Epub 2024 Sep 20. Br J Pharmacol. 2024. PMID: 39491825 Review.
Dynamics of the human bile acid metabolome during weight loss.
Schmid A, Liebisch G, Burkhardt R, Belikan H, Köhler S, Steger D, Schweitzer L, Pons-Kühnemann J, Karrasch T, Schäffler A. Schmid A, et al. Among authors: burkhardt r. Sci Rep. 2024 Oct 28;14(1):25743. doi: 10.1038/s41598-024-75831-1. Sci Rep. 2024. PMID: 39468179 Free PMC article.
351 results