Finamore C - Search Results

1

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.

Finamore C, Baronissi G, Marchianò S, Di Leva FS, Carino A, Monti MC, Limongelli V, Zampella A, Fiorucci S, Sepe V. Finamore C, et al. Molecules. 2019 Mar 16;24(6):1043. doi: 10.3390/molecules24061043. Molecules. 2019. PMID: 30884797 Free PMC article.

2

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

Festa C, Renga B, D'Amore C, Sepe V, Finamore C, De Marino S, Carino A, Cipriani S, Monti MC, Zampella A, Fiorucci S. Festa C, et al. Among authors: finamore c. J Med Chem. 2014 Oct 23;57(20):8477-95. doi: 10.1021/jm501273r. Epub 2014 Oct 9. J Med Chem. 2014. PMID: 25247751

3

Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.

Sepe V, Renga B, Festa C, Finamore C, Masullo D, Carino A, Cipriani S, Distrutti E, Fiorucci S, Zampella A. Sepe V, et al. Among authors: finamore c. Steroids. 2016 Jan;105:59-67. doi: 10.1016/j.steroids.2015.11.003. Epub 2015 Dec 1. Steroids. 2016. PMID: 26607331

4

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.

Sepe V, Festa C, Renga B, Carino A, Cipriani S, Finamore C, Masullo D, Del Gaudio F, Monti MC, Fiorucci S, Zampella A. Sepe V, et al. Among authors: finamore c. Sci Rep. 2016 Jan 7;6:19008. doi: 10.1038/srep19008. Sci Rep. 2016. PMID: 26740187 Free PMC article.

5

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.

Finamore C, Festa C, Renga B, Sepe V, Carino A, Masullo D, Biagioli M, Marchianò S, Capolupo A, Monti MC, Fiorucci S, Zampella A. Finamore C, et al. Sci Rep. 2016 Jul 6;6:29320. doi: 10.1038/srep29320. Sci Rep. 2016. PMID: 27381677 Free PMC article.

6

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.

De Marino S, Carino A, Masullo D, Finamore C, Marchianò S, Cipriani S, Di Leva FS, Catalanotti B, Novellino E, Limongelli V, Fiorucci S, Zampella A. De Marino S, et al. Among authors: finamore c. Sci Rep. 2017 Feb 24;7:43290. doi: 10.1038/srep43290. Sci Rep. 2017. PMID: 28233865 Free PMC article.

7

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.

Di Leva FS, Festa C, Carino A, De Marino S, Marchianò S, Di Marino D, Finamore C, Monti MC, Zampella A, Fiorucci S, Limongelli V. Di Leva FS, et al. Among authors: finamore c. Sci Rep. 2019 Feb 21;9(1):2504. doi: 10.1038/s41598-019-38840-z. Sci Rep. 2019. PMID: 30792450 Free PMC article.

8

Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.

Sepe V, Marchianò S, Finamore C, Baronissi G, Di Leva FS, Carino A, Biagioli M, Fiorucci C, Cassiano C, Monti MC, Del Gaudio F, Novellino E, Limongelli V, Fiorucci S, Zampella A. Sepe V, et al. Among authors: finamore c. ACS Med Chem Lett. 2018 Dec 6;10(4):407-412. doi: 10.1021/acsmedchemlett.8b00423. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996771 Free PMC article.

9

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

Festa C, Finamore C, Marchianò S, Di Leva FS, Carino A, Monti MC, Del Gaudio F, Ceccacci S, Limongelli V, Zampella A, Fiorucci S, De Marino S. Festa C, et al. Among authors: finamore c. ACS Med Chem Lett. 2019 Jan 10;10(4):504-510. doi: 10.1021/acsmedchemlett.8b00534. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996787 Free PMC article.

10

GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis.

Marino S, Finamore C, Biagioli M, Carino A, Marchianò S, Roselli R, Giorgio CD, Bordoni M, Di Leva FS, Novellino E, Cassiano C, Limongelli V, Zampella A, Festa C, Fiorucci S. Marino S, et al. Among authors: finamore c. ACS Med Chem Lett. 2020 Mar 2;11(5):818-824. doi: 10.1021/acsmedchemlett.9b00636. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435390 Free PMC article.

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