Maurer TS - Search Results

1

Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In Vivo.

Li Z, Di L, Maurer TS. Li Z, et al. Among authors: maurer ts. AAPS J. 2019 Mar 18;21(3):43. doi: 10.1208/s12248-019-0314-1. AAPS J. 2019. PMID: 30887138

2

Quantitative PK-PD model-based translational pharmacology of a novel kappa opioid receptor antagonist between rats and humans.

Chang C, Byon W, Lu Y, Jacobsen LK, Badura LL, Sawant-Basak A, Miller E, Liu J, Grimwood S, Wang EQ, Maurer TS. Chang C, et al. Among authors: maurer ts. AAPS J. 2011 Dec;13(4):565-75. doi: 10.1208/s12248-011-9296-3. Epub 2011 Aug 17. AAPS J. 2011. PMID: 21847689 Free PMC article.

3

Pharmacodynamic model of sodium-glucose transporter 2 (SGLT2) inhibition: implications for quantitative translational pharmacology.

Maurer TS, Ghosh A, Haddish-Berhane N, Sawant-Basak A, Boustany-Kari CM, She L, Leininger MT, Zhu T, Tugnait M, Yang X, Kimoto E, Mascitti V, Robinson RP. Maurer TS, et al. AAPS J. 2011 Dec;13(4):576-84. doi: 10.1208/s12248-011-9297-2. Epub 2011 Aug 26. AAPS J. 2011. PMID: 21870203 Free PMC article.

4

Impact of recovery on fraction unbound using equilibrium dialysis.

Di L, Umland JP, Trapa PE, Maurer TS. Di L, et al. Among authors: maurer ts. J Pharm Sci. 2012 Mar;101(3):1327-35. doi: 10.1002/jps.23013. Epub 2011 Dec 9. J Pharm Sci. 2012. PMID: 22161810

5

Toward a unified model of passive drug permeation II: the physiochemical determinants of unbound tissue distribution with applications to the design of hepatoselective glucokinase activators.

Ghosh A, Maurer TS, Litchfield J, Varma MV, Rotter C, Scialis R, Feng B, Tu M, Guimaraes CR, Scott DO. Ghosh A, et al. Among authors: maurer ts. Drug Metab Dispos. 2014 Oct;42(10):1599-610. doi: 10.1124/dmd.114.058032. Epub 2014 Jul 14. Drug Metab Dispos. 2014. PMID: 25024402

6

Volume of Distribution in Drug Design.

Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. Among authors: maurer ts. J Med Chem. 2015 Aug 13;58(15):5691-8. doi: 10.1021/acs.jmedchem.5b00201. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25799158

7

Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.

Li R, Maurer TS, Sweeney K, Barton HA. Li R, et al. Among authors: maurer ts. AAPS J. 2016 May;18(3):746-56. doi: 10.1208/s12248-016-9895-0. Epub 2016 Mar 7. AAPS J. 2016. PMID: 26951483 Free PMC article.

8

Model-Based Assessment of Plasma Citrate Flux Into the Liver: Implications for NaCT as a Therapeutic Target.

Li Z, Erion DM, Maurer TS. Li Z, et al. Among authors: maurer ts. CPT Pharmacometrics Syst Pharmacol. 2016 Mar;5(3):132-9. doi: 10.1002/psp4.12062. Epub 2016 Mar 4. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27069776 Free PMC article.

9

Passive drug permeation through membranes and cellular distribution.

Scott DO, Ghosh A, Di L, Maurer TS. Scott DO, et al. Among authors: maurer ts. Pharmacol Res. 2017 Mar;117:94-102. doi: 10.1016/j.phrs.2016.11.028. Epub 2016 Nov 24. Pharmacol Res. 2017. PMID: 27890815 Review.

10

In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey.

Trapa PE, Beaumont K, Atkinson K, Eng H, King-Ahmad A, Scott DO, Maurer TS, Di L. Trapa PE, et al. Among authors: maurer ts. J Pharm Sci. 2017 Mar;106(3):898-905. doi: 10.1016/j.xphs.2016.12.001. Epub 2016 Dec 18. J Pharm Sci. 2017. PMID: 27998705

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