Lokhorst HM - Search Results

1

T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells.

Pont MJ, Oostvogels R, van Bergen CAM, van der Meijden ED, Honders MW, Bliss S, Jongsma MLM, Lokhorst HM, Falkenburg JHF, Mutis T, Griffioen M, Spaapen RM. Pont MJ, et al. Among authors: lokhorst hm. Cancer Immunol Res. 2019 May;7(5):797-804. doi: 10.1158/2326-6066.CIR-18-0137. Epub 2019 Mar 19. Cancer Immunol Res. 2019. PMID: 30890530

2

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis.

Spaapen RM, Lokhorst HM, van den Oudenalder K, Otterud BE, Dolstra H, Leppert MF, Minnema MC, Bloem AC, Mutis T. Spaapen RM, et al. Among authors: lokhorst hm. J Exp Med. 2008 Nov 24;205(12):2863-72. doi: 10.1084/jem.20080713. Epub 2008 Nov 10. J Exp Med. 2008. PMID: 19001137 Free PMC article.

3

Rapid identification of clinical relevant minor histocompatibility antigens via genome-wide zygosity-genotype correlation analysis.

Spaapen RM, de Kort RA, van den Oudenalder K, van Elk M, Bloem AC, Lokhorst HM, Mutis T. Spaapen RM, et al. Among authors: lokhorst hm. Clin Cancer Res. 2009 Dec 1;15(23):7137-43. doi: 10.1158/1078-0432.CCR-09-1914. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934307

4

Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen.

Spaapen RM, Groen RW, van den Oudenalder K, Guichelaar T, van Elk M, Aarts-Riemens T, Bloem AC, Storm G, Martens AC, Lokhorst HM, Mutis T. Spaapen RM, et al. Among authors: lokhorst hm. Clin Cancer Res. 2010 Nov 15;16(22):5481-8. doi: 10.1158/1078-0432.CCR-10-1340. Epub 2010 Nov 9. Clin Cancer Res. 2010. PMID: 21062930

5

Rebuilding human leukocyte antigen class II-restricted minor histocompatibility antigen specificity in recall antigen-specific T cells by adoptive T cell receptor transfer: implications for adoptive immunotherapy.

Spaapen R, van den Oudenalder K, Ivanov R, Bloem A, Lokhorst H, Mutis T. Spaapen R, et al. Clin Cancer Res. 2007 Jul 1;13(13):4009-15. doi: 10.1158/1078-0432.CCR-07-0286. Clin Cancer Res. 2007. PMID: 17606735

6

Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes.

Hoppes R, Oostvogels R, Luimstra JJ, Wals K, Toebes M, Bies L, Ekkebus R, Rijal P, Celie PH, Huang JH, Emmelot ME, Spaapen RM, Lokhorst H, Schumacher TN, Mutis T, Rodenko B, Ovaa H. Hoppes R, et al. J Immunol. 2014 Nov 15;193(10):4803-13. doi: 10.4049/jimmunol.1400800. Epub 2014 Oct 13. J Immunol. 2014. PMID: 25311806 Free PMC article.

7

Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1.

Oostvogels R, Minnema MC, van Elk M, Spaapen RM, te Raa GD, Giovannone B, Buijs A, van Baarle D, Kater AP, Griffioen M, Spierings E, Lokhorst HM, Mutis T. Oostvogels R, et al. Among authors: lokhorst hm. Leukemia. 2013 Mar;27(3):642-9. doi: 10.1038/leu.2012.277. Epub 2012 Oct 1. Leukemia. 2013. PMID: 23079962 Free PMC article.

8

Human regulatory T cells do not suppress the antitumor immunity in the bone marrow: a role for bone marrow stromal cells in neutralizing regulatory T cells.

Guichelaar T, Emmelot ME, Rozemuller H, Martini B, Groen RW, Storm G, Lokhorst HM, Martens AC, Mutis T. Guichelaar T, et al. Among authors: lokhorst hm. Clin Cancer Res. 2013 Mar 15;19(6):1467-75. doi: 10.1158/1078-0432.CCR-12-2177. Epub 2013 Feb 4. Clin Cancer Res. 2013. PMID: 23382115

9

Identification of minor histocompatibility antigens based on the 1000 Genomes Project.

Oostvogels R, Lokhorst HM, Minnema MC, van Elk M, van den Oudenalder K, Spierings E, Mutis T, Spaapen RM. Oostvogels R, et al. Among authors: lokhorst hm. Haematologica. 2014 Dec;99(12):1854-9. doi: 10.3324/haematol.2014.109801. Epub 2014 Aug 22. Haematologica. 2014. PMID: 25150256 Free PMC article.

10

Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells.

Drent E, Poels R, Ruiter R, van de Donk NWCJ, Zweegman S, Yuan H, de Bruijn J, Sadelain M, Lokhorst HM, Groen RWJ, Mutis T, Themeli M. Drent E, et al. Among authors: lokhorst hm. Clin Cancer Res. 2019 Jul 1;25(13):4014-4025. doi: 10.1158/1078-0432.CCR-18-2559. Epub 2019 Apr 12. Clin Cancer Res. 2019. PMID: 30979735 Free PMC article.

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