Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1G93A mice.
Sawada A, Wang S, Jian M, Leem J, Wackerbarth J, Egawa J, Schilling JM, Platoshyn O, Zemljic-Harpf A, Roth DM, Patel HH, Patel PM, Marsala M, Head BP.
Sawada A, et al.
FASEB J. 2019 Jun;33(6):7545-7554. doi: 10.1096/fj.201802652RR. Epub 2019 Mar 20.
FASEB J. 2019.
PMID: 30894019
Free PMC article.
These findings demonstrate that SynCav1 delays disease progression in a mouse model of ALS, potentially by preserving or restoring NTR expression and localization to MLRs.-Sawada, A., Wang, S., Jian, M., Leem, J., Wackerbarth, J., Egawa, J., Schilling, J. M., …
These findings demonstrate that SynCav1 delays disease progression in a mouse model of ALS, potentially by preserving or restoring NT …