Hadden MK - Search Results

1

Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitors.

Pace JR, Teske KA, Chau LQ, Dash RC, Zaino AM, Wechsler-Reya RJ, Hadden MK. Pace JR, et al. Among authors: hadden mk. J Med Chem. 2019 Apr 25;62(8):3873-3885. doi: 10.1021/acs.jmedchem.8b01283. Epub 2019 Apr 5. J Med Chem. 2019. PMID: 30896941 Free PMC article.

2

Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold.

Hadden MK, Hill SA, Davenport J, Matts RL, Blagg BS. Hadden MK, et al. Bioorg Med Chem. 2009 Jan 15;17(2):634-40. doi: 10.1016/j.bmc.2008.11.064. Epub 2008 Dec 3. Bioorg Med Chem. 2009. PMID: 19101151 Free PMC article.

3

Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy.

Orwig KS, Lassetter MR, Hadden MK, Dix TA. Orwig KS, et al. Among authors: hadden mk. J Med Chem. 2009 Apr 9;52(7):1803-13. doi: 10.1021/jm801072v. J Med Chem. 2009. PMID: 19290594

4

Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway.

DeBerardinis AM, Banerjee U, Miller M, Lemieux S, Hadden MK. DeBerardinis AM, et al. Among authors: hadden mk. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4859-63. doi: 10.1016/j.bmcl.2012.05.037. Epub 2012 May 23. Bioorg Med Chem Lett. 2012. PMID: 22687748

5

Oncoepigenomics: making histone lysine methylation count.

Decarlo D, Hadden MK. Decarlo D, et al. Among authors: hadden mk. Eur J Med Chem. 2012 Oct;56:179-94. doi: 10.1016/j.ejmech.2012.08.010. Epub 2012 Aug 11. Eur J Med Chem. 2012. PMID: 22975593 Review.

6

Targeting the fibroblast growth factor receptors for the treatment of cancer.

Lemieux SM, Hadden MK. Lemieux SM, et al. Among authors: hadden mk. Anticancer Agents Med Chem. 2013 Jun;13(5):748-61. doi: 10.2174/18715206113139990080. Anticancer Agents Med Chem. 2013. PMID: 23272905 Review.

7

Hedgehog pathway inhibitors: a patent review (2009--present).

Hadden MK. Hadden MK. Expert Opin Ther Pat. 2013 Mar;23(3):345-61. doi: 10.1517/13543776.2013.757304. Epub 2013 Jan 8. Expert Opin Ther Pat. 2013. PMID: 23294277 Review.

8

Analogues of the Inhoffen-Lythgoe diol with anti-proliferative activity.

DeBerardinis AM, Lemieux S, Hadden MK. DeBerardinis AM, et al. Among authors: hadden mk. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5367-70. doi: 10.1016/j.bmcl.2013.07.054. Epub 2013 Jul 31. Bioorg Med Chem Lett. 2013. PMID: 23972439

9

Hedgehog pathway agonism: therapeutic potential and small-molecule development.

Hadden MK. Hadden MK. ChemMedChem. 2014 Jan;9(1):27-37. doi: 10.1002/cmdc.201300358. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203435 Review.

10

Structure-activity relationships for vitamin D3-based aromatic a-ring analogues as hedgehog pathway inhibitors.

Deberardinis AM, Madden DJ, Banerjee U, Sail V, Raccuia DS, De Carlo D, Lemieux SM, Meares A, Hadden MK. Deberardinis AM, et al. Among authors: hadden mk. J Med Chem. 2014 May 8;57(9):3724-36. doi: 10.1021/jm401812d. Epub 2014 Apr 28. J Med Chem. 2014. PMID: 24730984

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