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Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
Zimmerman M, McDonald SL, Ho-Liang HP, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS, Zhang D, Nathan CF, Dartois V, Aubé J. Zimmerman M, et al. Among authors: porubsky p. J Antibiot (Tokyo). 2019 Jun;72(6):469-475. doi: 10.1038/s41429-019-0167-y. Epub 2019 Mar 22. J Antibiot (Tokyo). 2019. PMID: 30903100 Free PMC article.
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Lopez Quezada L, Somersan S, Warrier T, Little D, Pingle M, Zhang D, Ballinger E, Zimmerman M, Dartois V, Hanson P, Mitscher LA, Porubsky P, Rogers S, Schoenen FJ, Nathan C, Aubé J. Gold B, et al. Among authors: porubsky p. J Med Chem. 2016 Jul 14;59(13):6027-44. doi: 10.1021/acs.jmedchem.5b01833. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27144688 Free PMC article.
Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis.
Goller CC, Arshad M, Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Neuenswander B, Porubsky P, Maki BE, Rogers SA, Schoenen F, Seed PC. Goller CC, et al. Among authors: porubsky p. PLoS One. 2014 Jul 1;9(7):e96054. doi: 10.1371/journal.pone.0096054. eCollection 2014. PLoS One. 2014. PMID: 24983234 Free PMC article.
Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening.
Spicer T, Fernandez-Vega V, Chase P, Scampavia L, To J, Dalton JP, Da Silva FL, Skinner-Adams TS, Gardiner DL, Trenholme KR, Brown CL, Ghosh P, Porubsky P, Wang JL, Whipple DA, Schoenen FJ, Hodder P. Spicer T, et al. Among authors: porubsky p. J Biomol Screen. 2014 Aug;19(7):1107-15. doi: 10.1177/1087057114525852. Epub 2014 Mar 11. J Biomol Screen. 2014. PMID: 24619116 Free PMC article.
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways.
Chou TF, Brown SJ, Minond D, Nordin BE, Li K, Jones AC, Chase P, Porubsky PR, Stoltz BM, Schoenen FJ, Patricelli MP, Hodder P, Rosen H, Deshaies RJ. Chou TF, et al. Among authors: porubsky pr. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4834-9. doi: 10.1073/pnas.1015312108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383145 Free PMC article.
Exploring chemical diversity via a modular reaction pairing strategy.
Loh JK, Yoon SY, Samarakoon TB, Rolfe A, Porubsky P, Neuenswander B, Lushington GH, Hanson PR. Loh JK, et al. Among authors: porubsky p. Beilstein J Org Chem. 2012;8:1293-302. doi: 10.3762/bjoc.8.147. Epub 2012 Aug 15. Beilstein J Org Chem. 2012. PMID: 23019462 Free PMC article.
31 results