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RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.
Alkasalias T, Alexeyenko A, Hennig K, Danielsson F, Lebbink RJ, Fielden M, Turunen SP, Lehti K, Kashuba V, Madapura HS, Bozoky B, Lundberg E, Balland M, Guvén H, Klein G, Gad AK, Pavlova T. Alkasalias T, et al. Among authors: turunen sp. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1413-E1421. doi: 10.1073/pnas.1621161114. Epub 2017 Feb 7. Proc Natl Acad Sci U S A. 2017. PMID: 28174275 Free PMC article.
Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.
Le Joncour V, Filppu P, Hyvönen M, Holopainen M, Turunen SP, Sihto H, Burghardt I, Joensuu H, Tynninen O, Jääskeläinen J, Weller M, Lehti K, Käkelä R, Laakkonen P. Le Joncour V, et al. Among authors: turunen sp. EMBO Mol Med. 2019 Jun;11(6):e9034. doi: 10.15252/emmm.201809034. EMBO Mol Med. 2019. PMID: 31068339 Free PMC article.
Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer.
Moyano-Galceran L, Pietilä EA, Turunen SP, Corvigno S, Hjerpe E, Bulanova D, Joneborg U, Alkasalias T, Miki Y, Yashiro M, Chernenko A, Jukonen J, Singh M, Dahlstrand H, Carlson JW, Lehti K. Moyano-Galceran L, et al. Among authors: turunen sp. EMBO Mol Med. 2020 Apr 7;12(4):e11177. doi: 10.15252/emmm.201911177. Epub 2020 Mar 2. EMBO Mol Med. 2020. PMID: 32115889 Free PMC article.
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.
Pietilä EA, Gonzalez-Molina J, Moyano-Galceran L, Jamalzadeh S, Zhang K, Lehtinen L, Turunen SP, Martins TA, Gultekin O, Lamminen T, Kaipio K, Joneborg U, Hynninen J, Hietanen S, Grénman S, Lehtonen R, Hautaniemi S, Carpén O, Carlson JW, Lehti K. Pietilä EA, et al. Among authors: turunen sp. Nat Commun. 2021 Jun 23;12(1):3904. doi: 10.1038/s41467-021-24009-8. Nat Commun. 2021. PMID: 34162871 Free PMC article.
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