Costi MP - Search Results

1

Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.

Linciano P, Pozzi C, Iacono LD, di Pisa F, Landi G, Bonucci A, Gul S, Kuzikov M, Ellinger B, Witt G, Santarem N, Baptista C, Franco C, Moraes CB, Müller W, Wittig U, Luciani R, Sesenna A, Quotadamo A, Ferrari S, Pöhner I, Cordeiro-da-Silva A, Mangani S, Costantino L, Costi MP. Linciano P, et al. Among authors: costi mp. J Med Chem. 2019 Apr 25;62(8):3989-4012. doi: 10.1021/acs.jmedchem.8b02021. Epub 2019 Apr 9. J Med Chem. 2019. PMID: 30908048

2

Deciphering Host-Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance.

Tagliazucchi L, Pinetti D, Genovese F, Malpezzi G, Perea Martinez A, Manzano JI, García-Hernández R, Cole AR, Kwon BR, Aiello D, Brooks BW, Thoré ESJ, Bertram MG, Gamarro F, Costi MP. Tagliazucchi L, et al. Among authors: costi mp. ACS Infect Dis. 2024 Sep 13;10(9):3202-3221. doi: 10.1021/acsinfecdis.4c00185. Epub 2024 Aug 1. ACS Infect Dis. 2024. PMID: 39088331

3

Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations.

Ghelli S, Rastelli G, Barlocco D, Rinaldi M, Tondi D, Pecorari P, Costi MP. Ghelli S, et al. Among authors: costi mp. Bioorg Med Chem. 1996 Oct;4(10):1783-94. doi: 10.1016/0968-0896(96)00193-9. Bioorg Med Chem. 1996. PMID: 8931948

4

Thymidylate synthase inhibition: a structure-based rationale for drug design.

Costi MP. Costi MP. Med Res Rev. 1998 Jan;18(1):21-42. doi: 10.1002/(sici)1098-1128(199801)18:1<21::aid-med2>3.0.co;2-u. Med Res Rev. 1998. PMID: 9436180 Review.

5

Update on antifolate drugs targets.

Costi MP, Ferrari S. Costi MP, et al. Curr Drug Targets. 2001 Jun;2(2):135-66. doi: 10.2174/1389450013348669. Curr Drug Targets. 2001. PMID: 11469716 Review.

6

ortho-Halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity.

Ghelli S, Rinaldi M, Barlocco D, Gelain A, Pecorari P, Tondi D, Rastelli G, Costi MP. Ghelli S, et al. Among authors: costi mp. Bioorg Med Chem. 2003 Mar 20;11(6):951-63. doi: 10.1016/s0968-0896(02)00541-2. Bioorg Med Chem. 2003. PMID: 12614880

7

Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.

Buzzoni V, Blazquez J, Ferrari S, Calò S, Venturelli A, Costi MP. Buzzoni V, et al. Among authors: costi mp. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3979-83. doi: 10.1016/j.bmcl.2004.05.054. Bioorg Med Chem Lett. 2004. PMID: 15225711

8

Improving specificity vs bacterial thymidylate synthases through N-dansyl modulation of didansyltyrosine.

Tondi D, Venturelli A, Ferrari S, Ghelli S, Costi MP. Tondi D, et al. Among authors: costi mp. J Med Chem. 2005 Feb 24;48(4):913-6. doi: 10.1021/jm0491445. J Med Chem. 2005. PMID: 15715461

9

Thymidylate synthase structure, function and implication in drug discovery.

Costi MP, Ferrari S, Venturelli A, Calò S, Tondi D, Barlocco D. Costi MP, et al. Curr Med Chem. 2005;12(19):2241-58. doi: 10.2174/0929867054864868. Curr Med Chem. 2005. PMID: 16178783 Review.

10

Antibacterial agent discovery using thymidylate synthase biolibrary screening.

Costi MP, Gelain A, Barlocco D, Ghelli S, Soragni F, Reniero F, Rossi T, Ruberto A, Guillou C, Cavazzuti A, Casolari C, Ferrari S. Costi MP, et al. J Med Chem. 2006 Oct 5;49(20):5958-68. doi: 10.1021/jm051187d. J Med Chem. 2006. PMID: 17004711

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