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Page 1
Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
Büller NV, Rosekrans SL, Metcalfe C, Heijmans J, van Dop WA, Fessler E, Jansen M, Ahn C, Vermeulen JL, Westendorp BF, Robanus-Maandag EC, Offerhaus GJ, Medema JP, D'Haens GR, Wildenberg ME, de Sauvage FJ, Muncan V, van den Brink GR. Büller NV, et al. Among authors: westendorp bf. Gastroenterology. 2015 Jan;148(1):170-180.e6. doi: 10.1053/j.gastro.2014.10.006. Epub 2014 Oct 13. Gastroenterology. 2015. PMID: 25307863
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response.
Westendorp BF, Büller NVJA, Karpus ON, van Dop WA, Koster J, Versteeg R, Koelink PJ, Snel CY, Meisner S, Roelofs JJTH, Uhmann A, Ver Loren van Themaat E, Heijmans J, Hahn H, Muncan V, Wildenberg ME, van den Brink GR. Westendorp BF, et al. Cell Mol Gastroenterol Hepatol. 2017 Sep 5;5(1):67-82.e1. doi: 10.1016/j.jcmgh.2017.08.004. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29276753 Free PMC article.
Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation.
van Lidth de Jeude JF, Spaan CN, Meijer BJ, Smit WL, Soeratram TTD, Wielenga MCB, Westendorp BF, Lee AS, Meisner S, Vermeulen JLM, Wildenberg ME, van den Brink GR, Muncan V, Heijmans J. van Lidth de Jeude JF, et al. Among authors: westendorp bf. Cancer Res. 2018 Nov 1;78(21):6098-6106. doi: 10.1158/0008-5472.CAN-17-3600. Epub 2018 Sep 19. Cancer Res. 2018. PMID: 30232220 Free PMC article.
Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2.
Meijer BJ, Smit WL, Koelink PJ, Westendorp BF, de Boer RJ, van der Meer JHM, Vermeulen JLM, Paton JC, Paton AW, Qin J, Dekker E, Muncan V, van den Brink GR, Heijmans J. Meijer BJ, et al. Among authors: westendorp bf. Sci Rep. 2021 May 10;11(1):9892. doi: 10.1038/s41598-021-89326-w. Sci Rep. 2021. PMID: 33972635 Free PMC article.
Loss of bone morphogenetic protein signaling in fibroblasts results in CXCL12-driven serrated polyp development.
Ouahoud S, Westendorp BF, Voorneveld PW, Abudukelimu S, Koelink PJ, Pascual Garcia E, Buuren JFI, Harryvan TJ, Lenos KJ, van Wezel T, Offerhaus JA, Fariña-Sarasqueta A, Crobach S, Slingerland M, Hardwick JCH, Hawinkels LJAC. Ouahoud S, et al. Among authors: westendorp bf. J Gastroenterol. 2023 Jan;58(1):25-43. doi: 10.1007/s00535-022-01928-x. Epub 2022 Nov 3. J Gastroenterol. 2023. PMID: 36326956 Free PMC article.
CD95 signaling in colorectal cancer.
Hoogwater FJ, Steller EJ, Westendorp BF, Borel Rinkes IH, Kranenburg O. Hoogwater FJ, et al. Among authors: westendorp bf. Biochim Biophys Acta. 2012 Aug;1826(1):189-98. doi: 10.1016/j.bbcan.2012.03.007. Epub 2012 Mar 31. Biochim Biophys Acta. 2012. PMID: 22498253 Review.
Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.
Hoogwater FJ, Nijkamp MW, Smakman N, Steller EJ, Emmink BL, Westendorp BF, Raats DA, Sprick MR, Schaefer U, Van Houdt WJ, De Bruijn MT, Schackmann RC, Derksen PW, Medema JP, Walczak H, Borel Rinkes IH, Kranenburg O. Hoogwater FJ, et al. Among authors: westendorp bf. Gastroenterology. 2010 Jun;138(7):2357-67. doi: 10.1053/j.gastro.2010.02.046. Epub 2010 Feb 23. Gastroenterology. 2010. PMID: 20188103