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Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.
Tomar D, Jaña F, Dong Z, Quinn WJ 3rd, Jadiya P, Breves SL, Daw CC, Srikantan S, Shanmughapriya S, Nemani N, Carvalho E, Tripathi A, Worth AM, Zhang X, Razmpour R, Seelam A, Rhode S, Mehta AV, Murray M, Slade D, Ramirez SH, Mishra P, Gerhard GS, Caplan J, Norton L, Sharma K, Rajan S, Balciunas D, Wijesinghe DS, Ahima RS, Baur JA, Madesh M. Tomar D, et al. Among authors: wijesinghe ds. Cell Rep. 2019 Mar 26;26(13):3709-3725.e7. doi: 10.1016/j.celrep.2019.02.107. Cell Rep. 2019. PMID: 30917323 Free PMC article.
Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide.
Spijkers LJ, van den Akker RF, Janssen BJ, Debets JJ, De Mey JG, Stroes ES, van den Born BJ, Wijesinghe DS, Chalfant CE, MacAleese L, Eijkel GB, Heeren RM, Alewijnse AE, Peters SL. Spijkers LJ, et al. Among authors: wijesinghe ds. PLoS One. 2011;6(7):e21817. doi: 10.1371/journal.pone.0021817. Epub 2011 Jul 19. PLoS One. 2011. PMID: 21818267 Free PMC article.
Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension.
Gomez-Arroyo J, Mizuno S, Szczepanek K, Van Tassell B, Natarajan R, dos Remedios CG, Drake JI, Farkas L, Kraskauskas D, Wijesinghe DS, Chalfant CE, Bigbee J, Abbate A, Lesnefsky EJ, Bogaard HJ, Voelkel NF. Gomez-Arroyo J, et al. Among authors: wijesinghe ds. Circ Heart Fail. 2013 Jan;6(1):136-44. doi: 10.1161/CIRCHEARTFAILURE.111.966127. Epub 2012 Nov 14. Circ Heart Fail. 2013. PMID: 23152488 Free PMC article.
The role of ceramide-1-phosphate in biological functions.
Hoeferlin LA, Wijesinghe DS, Chalfant CE. Hoeferlin LA, et al. Among authors: wijesinghe ds. Handb Exp Pharmacol. 2013;(215):153-66. doi: 10.1007/978-3-7091-1368-4_8. Handb Exp Pharmacol. 2013. PMID: 23579454 Free PMC article. Review.
73 results