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In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sun X, et al. Among authors: rotti pg. Sci Transl Med. 2019 Mar 27;11(485):eaau7531. doi: 10.1126/scitranslmed.aau7531. Sci Transl Med. 2019. PMID: 30918114 Free PMC article.
Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.
Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF. Rosen BH, et al. Among authors: rotti pg. Am J Respir Crit Care Med. 2018 May 15;197(10):1308-1318. doi: 10.1164/rccm.201708-1616OC. Am J Respir Crit Care Med. 2018. PMID: 29327941 Free PMC article.
Development of a polarized pancreatic ductular cell epithelium for physiological studies.
O'Malley Y, Rotti PG, Thornell IM, Vanegas Calderón OG, Febres-Aldana C, Durham K, Yao J, Li X, Zhu Z, Norris AW, Zabner J, Engelhardt JF, Uc A. O'Malley Y, et al. Among authors: rotti pg. J Appl Physiol (1985). 2018 Jul 1;125(1):97-106. doi: 10.1152/japplphysiol.00043.2018. Epub 2018 Mar 8. J Appl Physiol (1985). 2018. PMID: 29517421 Free PMC article.
Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.
Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF. Lynch TJ, et al. Among authors: rotti pg. Cell Stem Cell. 2018 May 3;22(5):653-667.e5. doi: 10.1016/j.stem.2018.03.017. Epub 2018 Apr 12. Cell Stem Cell. 2018. PMID: 29656941 Free PMC article.
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.
Tyler SR, Rotti PG, Sun X, Yi Y, Xie W, Winter MC, Flamme-Wiese MJ, Tucker BA, Mullins RF, Norris AW, Engelhardt JF. Tyler SR, et al. Among authors: rotti pg. Cell Rep. 2019 Feb 12;26(7):1951-1964.e8. doi: 10.1016/j.celrep.2019.01.063. Cell Rep. 2019. PMID: 30759402 Free PMC article.
In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human Pancreas.
White MG, Maheshwari RR, Anderson SJ, Berlinguer-Palmini R, Jones C, Richardson SJ, Rotti PG, Armour SL, Ding Y, Krasnogor N, Engelhardt JF, Gray MA, Morgan NG, Shaw JAM. White MG, et al. Among authors: rotti pg. J Clin Endocrinol Metab. 2020 May 1;105(5):1366-74. doi: 10.1210/clinem/dgz209. J Clin Endocrinol Metab. 2020. PMID: 31748811 Free PMC article.
15 results