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In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sun X, et al. Among authors: tran dm. Sci Transl Med. 2019 Mar 27;11(485):eaau7531. doi: 10.1126/scitranslmed.aau7531. Sci Transl Med. 2019. PMID: 30918114 Free PMC article.
Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease.
Ernst JT, Neubert T, Liu M, Sperry S, Zuccola H, Turnbull A, Fleck B, Kargo W, Woody L, Chiang P, Tran D, Chen W, Snyder P, Alcacio T, Nezami A, Reynolds J, Alvi K, Goulet L, Stamos D. Ernst JT, et al. J Med Chem. 2014 Apr 24;57(8):3382-400. doi: 10.1021/jm500042s. Epub 2014 Apr 10. J Med Chem. 2014. PMID: 24673104
Long-term risk of mortality and loss to follow-up in children and adolescents on antiretroviral therapy in Asia.
Nimkar S, Kinikar A, Mave V, Khol V, Du QT, Nguyen L, Ounchanum P, Nguyen DQ, Puthanakit T, Kosalaraks P, Chokephaibulkit K, Sudjaritruk T, Muktiarti D, Kumarasamy N, Yusoff NKN, Mohamed T, Wati D, Alam A, Fong S, Nallusamy R, Suwanlerk T, Sohn A, Kariminia A; TREAT Asia Pediatric HIV Observational Database of IeDEA Asia‐Pacific. Nimkar S, et al. HIV Med. 2024 Sep 26. doi: 10.1111/hiv.13718. Online ahead of print. HIV Med. 2024. PMID: 39324422
141 results