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Leflunomide regulates c-Myc expression in myeloma cells through PIM targeting.
Buettner R, Morales C, Caserta E, Troadec E, Gunes EG, Viola D, Khalife J, Li H, Keats JJ, Christofferson A, Wu X, Synold TW, Palmer J, Sanchez JF, Pozhitkov A, Vaidehi N, Marcucci G, Krishnan A, Rosenzweig MA, Pichiorri F, Rosen ST. Buettner R, et al. Among authors: rosenzweig ma. Blood Adv. 2019 Apr 9;3(7):1027-1032. doi: 10.1182/bloodadvances.2018027227. Blood Adv. 2019. PMID: 30940637 Free PMC article.
Daratumumab induces CD38 internalization and impairs myeloma cell adhesion.
Ghose J, Viola D, Terrazas C, Caserta E, Troadec E, Khalife J, Gunes EG, Sanchez J, McDonald T, Marcucci G, Kaur B, Rosenzweig M, Keats J, Rosen S, Krishnan A, Satoskar AR, Hofmeister CC, Pichiorri F. Ghose J, et al. Oncoimmunology. 2018 Jul 23;7(10):e1486948. doi: 10.1080/2162402X.2018.1486948. eCollection 2018. Oncoimmunology. 2018. PMID: 30288349 Free PMC article.
Repurposing leflunomide for relapsed/refractory multiple myeloma: a phase 1 study.
Rosenzweig M, Palmer J, Tsai NC, Synold T, Wu X, Tao S, Hammond SN, Buettner R, Duarte L, Htut M, Karanes C, Nathwani N, Pichiorri F, Sahebi F, Sanchez JF, Chowdhury A, Krishnan A, Forman SJ, Rosen ST. Rosenzweig M, et al. Leuk Lymphoma. 2020 Jul;61(7):1669-1677. doi: 10.1080/10428194.2020.1742900. Epub 2020 Apr 8. Leuk Lymphoma. 2020. PMID: 32268821 Free PMC article. Clinical Trial.
Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting.
Viola D, Dona A, Caserta E, Troadec E, Besi F, McDonald T, Ghoda L, Gunes EG, Sanchez JF, Khalife J, Martella M, Karanes C, Htut M, Wang X, Rosenzweig M, Chowdhury A, Sborov D, Miles RR, Yazaki PJ, Ebner T, Hofmeister CC, Forman SJ, Rosen ST, Marcucci G, Shively J, Keats JJ, Krishnan A, Pichiorri F. Viola D, et al. Leukemia. 2021 Jan;35(1):189-200. doi: 10.1038/s41375-020-0810-4. Epub 2020 Apr 16. Leukemia. 2021. PMID: 32296125 Free PMC article.
Toxicities Associated With Metformin/Ritonavir Combination Treatment in Relapsed/Refractory Multiple Myeloma.
Nathwani N, Palmer J, Synold TW, Salehian B, Rosenzweig M, Sanchez JF, Hammond SN, Adekola K, Tomarchio V, Chowdhury A, Karanes C, Htut M, Sahebi F, Siddiqi T, Krishnan A, Forman SJ, Rosen ST. Nathwani N, et al. Clin Lymphoma Myeloma Leuk. 2020 Oct;20(10):e667-e672. doi: 10.1016/j.clml.2020.05.017. Epub 2020 May 29. Clin Lymphoma Myeloma Leuk. 2020. PMID: 32631779 Free PMC article. No abstract available.
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