Chuprun JK - Search Results

1

Alteration of myocardial GRK2 produces a global metabolic phenotype.

Woodall BP, Gresham KS, Woodall MA, Valenti MC, Cannavo A, Pfleger J, Chuprun JK, Drosatos K, Koch WJ. Woodall BP, et al. Among authors: chuprun jk. JCI Insight. 2019 Apr 4;5(10):e123848. doi: 10.1172/jci.insight.123848. JCI Insight. 2019. PMID: 30946029 Free PMC article.

2

GRK2 in the heart: a GPCR kinase and beyond.

Huang ZM, Gao E, Chuprun JK, Koch WJ. Huang ZM, et al. Among authors: chuprun jk. Antioxid Redox Signal. 2014 Nov 10;21(14):2032-43. doi: 10.1089/ars.2014.5876. Epub 2014 May 13. Antioxid Redox Signal. 2014. PMID: 24702056 Free PMC article. Review.

3

GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels.

Sato PY, Chuprun JK, Ibetti J, Cannavo A, Drosatos K, Elrod JW, Koch WJ. Sato PY, et al. Among authors: chuprun jk. J Mol Cell Cardiol. 2015 Dec;89(Pt B):360-4. doi: 10.1016/j.yjmcc.2015.10.002. Epub 2015 Oct 23. J Mol Cell Cardiol. 2015. PMID: 26506135 Free PMC article.

4

Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac Hypertrophy.

Traynham CJ, Cannavo A, Zhou Y, Vouga AG, Woodall BP, Hullmann J, Ibetti J, Gold JI, Chuprun JK, Gao E, Koch WJ. Traynham CJ, et al. Among authors: chuprun jk. Circ Res. 2015 Dec 4;117(12):1001-12. doi: 10.1161/CIRCRESAHA.115.306961. Epub 2015 Oct 29. Circ Res. 2015. PMID: 26515328 Free PMC article.

5

A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload.

Bledzka KM, Manaserh IH, Grondolsky J, Pfleger J, Roy R, Gao E, Chuprun JK, Koch WJ, Schumacher SM. Bledzka KM, et al. Among authors: chuprun jk. J Mol Cell Cardiol. 2021 May;154:137-153. doi: 10.1016/j.yjmcc.2021.01.004. Epub 2021 Feb 4. J Mol Cell Cardiol. 2021. PMID: 33548241 Free PMC article.

6

Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.

Sato PY, Chuprun JK, Grisanti LA, Woodall MC, Brown BR, Roy R, Traynham CJ, Ibetti J, Lucchese AM, Yuan A, Drosatos K, Tilley DG, Gao E, Koch WJ. Sato PY, et al. Among authors: chuprun jk. Sci Signal. 2018 Dec 11;11(560):eaau0144. doi: 10.1126/scisignal.aau0144. Sci Signal. 2018. PMID: 30538174 Free PMC article.

7

Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction.

Schumacher SM, Gao E, Zhu W, Chen X, Chuprun JK, Feldman AM, Tesmer JJ, Koch WJ. Schumacher SM, et al. Among authors: chuprun jk. Sci Transl Med. 2015 Mar 4;7(277):277ra31. doi: 10.1126/scitranslmed.aaa0154. Sci Transl Med. 2015. PMID: 25739765 Free PMC article.

8

The evolving impact of g protein-coupled receptor kinases in cardiac health and disease.

Sato PY, Chuprun JK, Schwartz M, Koch WJ. Sato PY, et al. Among authors: chuprun jk. Physiol Rev. 2015 Apr;95(2):377-404. doi: 10.1152/physrev.00015.2014. Physiol Rev. 2015. PMID: 25834229 Free PMC article. Review.

9

A peptide of the RGS domain of GRK2 binds and inhibits Gα(q) to suppress pathological cardiac hypertrophy and dysfunction.

Schumacher SM, Gao E, Cohen M, Lieu M, Chuprun JK, Koch WJ. Schumacher SM, et al. Among authors: chuprun jk. Sci Signal. 2016 Mar 22;9(420):ra30. doi: 10.1126/scisignal.aae0549. Sci Signal. 2016. PMID: 27016525 Free PMC article.

10

GRK5 is a regulator of fibroblast activation and cardiac fibrosis.

Eguchi A, Coleman R, Gresham K, Gao E, Ibetti J, Chuprun JK, Koch WJ. Eguchi A, et al. Among authors: chuprun jk. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2012854118. doi: 10.1073/pnas.2012854118. Proc Natl Acad Sci U S A. 2021. PMID: 33500351 Free PMC article.

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