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Page 1
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T. Lytle NK, et al. Among authors: shima y. Cell. 2019 Apr 18;177(3):572-586.e22. doi: 10.1016/j.cell.2019.03.010. Epub 2019 Apr 4. Cell. 2019. PMID: 30955884 Free PMC article.
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T. Bajaj J, et al. Among authors: shima y. Nat Cancer. 2020 Apr;1(4):410-422. doi: 10.1038/s43018-020-0054-2. Epub 2020 Apr 20. Nat Cancer. 2020. PMID: 34109316 Free PMC article.
Deregulated transcription factors in leukemia.
Shima Y, Kitabayashi I. Shima Y, et al. Int J Hematol. 2011 Aug;94(2):134-141. doi: 10.1007/s12185-011-0905-9. Epub 2011 Aug 9. Int J Hematol. 2011. PMID: 21823042 Review.
MLL is essential for NUP98-HOXA9-induced leukemia.
Shima Y, Yumoto M, Katsumoto T, Kitabayashi I. Shima Y, et al. Leukemia. 2017 Oct;31(10):2200-2210. doi: 10.1038/leu.2017.62. Epub 2017 Feb 17. Leukemia. 2017. PMID: 28210005
A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
Machida Y, Nakagawa M, Matsunaga H, Yamaguchi M, Ogawara Y, Shima Y, Yamagata K, Katsumoto T, Hattori A, Itoh M, Seki T, Nishiya Y, Nakamura K, Suzuki K, Imaoka T, Baba D, Suzuki M, Sampetrean O, Saya H, Ichimura K, Kitabayashi I. Machida Y, et al. Among authors: shima y. Mol Cancer Ther. 2020 Feb;19(2):375-383. doi: 10.1158/1535-7163.MCT-18-1349. Epub 2019 Nov 14. Mol Cancer Ther. 2020. PMID: 31727689
811 results