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A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system.
Nat Commun. 2019 Apr 10;10(1):1668. doi: 10.1038/s41467-019-09656-2.
Nat Commun. 2019.
PMID: 30971695
Free PMC article.
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
LaFleur MW, Nguyen TH, Coxe MA, Miller BC, Yates KB, Gillis JE, Sen DR, Gaudiano EF, Al Abosy R, Freeman GJ, Haining WN, Sharpe AH.
LaFleur MW, et al. Among authors: coxe ma.
Nat Immunol. 2019 Oct;20(10):1335-1347. doi: 10.1038/s41590-019-0480-4. Epub 2019 Sep 16.
Nat Immunol. 2019.
PMID: 31527834
Free PMC article.
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In Vivo CRISPR Screening Reveals CHD7 as a Positive Regulator of Short-lived Effector Cells.
LaFleur MW, D'Andrea JM, Patterson DG, Streeter ISL, Coxe MA, Osborn JF, Milling LE, Tjokrosurjo Q, Gillis JE, Nguyen TH, Schwartz MA, Hacohen N, Doench JG, Sharpe AH.
LaFleur MW, et al. Among authors: coxe ma.
J Immunol. 2024 Nov 15;213(10):1528-1541. doi: 10.4049/jimmunol.2400213.
J Immunol. 2024.
PMID: 39373572
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