Lin YL - Search Results

1

An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans.

Chung S, Nguyen V, Lin YL, Lafrance-Vanasse J, Scales SJ, Lin K, Deng R, Williams K, Sperinde G, Li JJ, Zheng K, Sukumaran S, Tesar D, Ernst JA, Fischer S, Lazar GA, Prabhu S, Song A. Chung S, et al. Among authors: lin yl, lin k. MAbs. 2019 Jul;11(5):942-955. doi: 10.1080/19420862.2019.1605270. Epub 2019 Apr 29. MAbs. 2019. PMID: 30982394 Free PMC article.

2

Development of a label-free FcRn-mediated transcytosis assay for in vitro characterization of FcRn interactions with therapeutic antibodies and Fc-fusion proteins.

Chung S, Lin YL, Nguyen V, Kamen L, Zheng K, Vora B, Song A. Chung S, et al. Among authors: lin yl. J Immunol Methods. 2018 Nov;462:101-105. doi: 10.1016/j.jim.2018.07.004. Epub 2018 Jul 18. J Immunol Methods. 2018. PMID: 30030147

3

Methods for Functional Characterization of FcRn Interactions with Therapeutic Antibodies and Fc-Fusion Proteins.

Chung S, Lin YL, Nguyen V, Liu C. Chung S, et al. Among authors: lin yl. Methods Mol Biol. 2022;2313:295-303. doi: 10.1007/978-1-0716-1450-1_18. Methods Mol Biol. 2022. PMID: 34478146

4

Thaw-and-use target cells pre-labeled with calcein AM for antibody-dependent cell-mediated cytotoxicity assays.

Chung S, Nguyen V, Lin YL, Kamen L, Song A. Chung S, et al. Among authors: lin yl. J Immunol Methods. 2017 Aug;447:37-46. doi: 10.1016/j.jim.2017.04.005. Epub 2017 Apr 21. J Immunol Methods. 2017. PMID: 28434980

5

Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells.

Chung S, Lin YL, Reed C, Ng C, Cheng ZJ, Malavasi F, Yang J, Quarmby V, Song A. Chung S, et al. Among authors: lin yl. J Immunol Methods. 2014 May;407:63-75. doi: 10.1016/j.jim.2014.03.021. Epub 2014 Apr 3. J Immunol Methods. 2014. PMID: 24704820

6

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.

Lo M, Kim HS, Tong RK, Bainbridge TW, Vernes JM, Zhang Y, Lin YL, Chung S, Dennis MS, Zuchero YJ, Watts RJ, Couch JA, Meng YG, Atwal JK, Brezski RJ, Spiess C, Ernst JA. Lo M, et al. Among authors: lin yl. J Biol Chem. 2017 Mar 3;292(9):3900-3908. doi: 10.1074/jbc.M116.767749. Epub 2017 Jan 11. J Biol Chem. 2017. PMID: 28077575 Free PMC article.

7

Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.

Couch JA, Yu YJ, Zhang Y, Tarrant JM, Fuji RN, Meilandt WJ, Solanoy H, Tong RK, Hoyte K, Luk W, Lu Y, Gadkar K, Prabhu S, Ordonia BA, Nguyen Q, Lin Y, Lin Z, Balazs M, Scearce-Levie K, Ernst JA, Dennis MS, Watts RJ. Couch JA, et al. Sci Transl Med. 2013 May 1;5(183):183ra57, 1-12. doi: 10.1126/scitranslmed.3005338. Sci Transl Med. 2013. PMID: 23636093

8

Engineering upper hinge improves stability and effector function of a human IgG1.

Yan B, Boyd D, Kaschak T, Tsukuda J, Shen A, Lin Y, Chung S, Gupta P, Kamath A, Wong A, Vernes JM, Meng GY, Totpal K, Schaefer G, Jiang G, Nogal B, Emery C, Vanderlaan M, Carter P, Harris R, Amanullah A. Yan B, et al. J Biol Chem. 2012 Feb 17;287(8):5891-7. doi: 10.1074/jbc.M111.311811. Epub 2011 Dec 27. J Biol Chem. 2012. PMID: 22203673 Free PMC article.

9

Association of serum intact parathyroid hormone levels with sarcopenia in patients undergoing peritoneal dialysis.

Hsu BG, Wang CH, Tsai JP, Chen YH, Hung SC, Lin YL. Hsu BG, et al. Among authors: lin yl. Front Med (Lausanne). 2024 Oct 16;11:1487449. doi: 10.3389/fmed.2024.1487449. eCollection 2024. Front Med (Lausanne). 2024. PMID: 39478830 Free PMC article.

10

From emergence to endemicity of highly pathogenic H5 avian influenza viruses in Taiwan.

Li YT, Ko HY, Hughes J, Liu MT, Lin YL, Hampson K, Brunker K. Li YT, et al. Among authors: lin yl. Nat Commun. 2024 Oct 29;15(1):9348. doi: 10.1038/s41467-024-53816-y. Nat Commun. 2024. PMID: 39472594

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