Schepers H - Search Results

1

Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.

Mattes K, Geugien M, Korthuis PM, Brouwers-Vos AZ, Fehrmann RSN, Todorova TI, Steidl U, Vellenga E, Schepers H. Mattes K, et al. Among authors: schepers h. Exp Hematol. 2019 May;73:38-49.e7. doi: 10.1016/j.exphem.2019.03.003. Epub 2019 Apr 13. Exp Hematol. 2019. PMID: 30986495 Free article.

2

HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun.

Schepers H, Geugien M, van der Toorn M, Bryantsev AL, Kampinga HH, Eggen BJ, Vellenga E. Schepers H, et al. Exp Hematol. 2005 Jun;33(6):660-70. doi: 10.1016/j.exphem.2005.03.009. Exp Hematol. 2005. PMID: 15911090 Free article.

3

Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells.

van Gosliga D, Schepers H, Rizo A, van der Kolk D, Vellenga E, Schuringa JJ. van Gosliga D, et al. Among authors: schepers h. Exp Hematol. 2007 Oct;35(10):1538-49. doi: 10.1016/j.exphem.2007.07.001. Exp Hematol. 2007. PMID: 17889721 Free article.

4

Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases.

Fatrai S, Schepers H, Tadema H, Vellenga E, Daenen SM, Schuringa JJ. Fatrai S, et al. Among authors: schepers h. Exp Hematol. 2008 Oct;36(10):1254-65. doi: 10.1016/j.exphem.2008.04.015. Epub 2008 Jul 21. Exp Hematol. 2008. PMID: 18640764 Free article.

5

CITED2 affects leukemic cell survival by interfering with p53 activation.

Mattes K, Berger G, Geugien M, Vellenga E, Schepers H. Mattes K, et al. Among authors: schepers h. Cell Death Dis. 2017 Oct 26;8(10):e3132. doi: 10.1038/cddis.2017.548. Cell Death Dis. 2017. PMID: 29072699 Free PMC article.

6

Differential redox-regulation and mitochondrial dynamics in normal and leukemic hematopoietic stem cells: A potential window for leukemia therapy.

Mattes K, Vellenga E, Schepers H. Mattes K, et al. Among authors: schepers h. Crit Rev Oncol Hematol. 2019 Dec;144:102814. doi: 10.1016/j.critrevonc.2019.102814. Epub 2019 Sep 25. Crit Rev Oncol Hematol. 2019. PMID: 31593878 Free article. Review.

7

CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia.

Korthuis PM, Berger G, Bakker B, Rozenveld-Geugien M, Jaques J, de Haan G, Schuringa JJ, Vellenga E, Schepers H. Korthuis PM, et al. Among authors: schepers h. Leukemia. 2015 Mar;29(3):625-35. doi: 10.1038/leu.2014.259. Epub 2014 Sep 3. Leukemia. 2015. PMID: 25184385

8

Oncogenic Ras blocks transforming growth factor-beta-induced cell-cycle arrest by degradation of p27 through a MEK/Erk/SKP2-dependent pathway.

Schepers H, Wierenga AT, Eggen BJ, Vellenga E. Schepers H, et al. Exp Hematol. 2005 Jul;33(7):747-57. doi: 10.1016/j.exphem.2005.04.006. Exp Hematol. 2005. PMID: 15963850 Free article.

9

STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPalpha.

Wierenga AT, Schepers H, Moore MA, Vellenga E, Schuringa JJ. Wierenga AT, et al. Among authors: schepers h. Blood. 2006 Jun 1;107(11):4326-33. doi: 10.1182/blood-2005-11-4608. Epub 2006 Feb 2. Blood. 2006. PMID: 16455947 Free article.

10

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells.

Schepers H, van Gosliga D, Wierenga AT, Eggen BJ, Schuringa JJ, Vellenga E. Schepers H, et al. Blood. 2007 Oct 15;110(8):2880-8. doi: 10.1182/blood-2006-08-039073. Epub 2007 Jul 13. Blood. 2007. PMID: 17630355 Free article.

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