Pace P - Search Results

1

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides.

Bresciani A, Ontoria JM, Biancofiore I, Cellucci A, Ciammaichella A, Di Marco A, Ferrigno F, Francone A, Malancona S, Monteagudo E, Nizi E, Pace P, Ponzi S, Rossetti I, Veneziano M, Summa V, Harper S. Bresciani A, et al. Among authors: pace p. ACS Med Chem Lett. 2018 Nov 27;10(4):481-486. doi: 10.1021/acsmedchemlett.8b00517. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996783 Free PMC article.

2

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.

Ponzi S, Bresciani A, Kaiser M, Nardi V, Nizi E, Ontoria JM, Pace P, Paonessa G, Summa V, Harper S. Ponzi S, et al. Among authors: pace p. Bioorg Med Chem Lett. 2020 Apr 15;30(8):127052. doi: 10.1016/j.bmcl.2020.127052. Epub 2020 Feb 22. Bioorg Med Chem Lett. 2020. PMID: 32113841

3

Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.

Summa V, Petrocchi A, Pace P, Matassa VG, De Francesco R, Altamura S, Tomei L, Koch U, Neuner P. Summa V, et al. Among authors: pace p. J Med Chem. 2004 Jan 1;47(1):14-7. doi: 10.1021/jm0342109. J Med Chem. 2004. PMID: 14695815

4

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase.

Pace P, Nizi E, Pacini B, Pesci S, Matassa V, De Francesco R, Altamura S, Summa V. Pace P, et al. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3257-61. doi: 10.1016/j.bmcl.2004.03.087. Bioorg Med Chem Lett. 2004. PMID: 15149686

5

4,5-dihydroxypyrimidine carboxamides and N-alkyl-5-hydroxypyrimidinone carboxamides are potent, selective HIV integrase inhibitors with good pharmacokinetic profiles in preclinical species.

Summa V, Petrocchi A, Matassa VG, Gardelli C, Muraglia E, Rowley M, Paz OG, Laufer R, Monteagudo E, Pace P. Summa V, et al. Among authors: pace p. J Med Chem. 2006 Nov 16;49(23):6646-9. doi: 10.1021/jm060854f. J Med Chem. 2006. PMID: 17154493

6

Dihydroxypyrimidine-4-carboxamides as novel potent and selective HIV integrase inhibitors.

Pace P, Di Francesco ME, Gardelli C, Harper S, Muraglia E, Nizi E, Orvieto F, Petrocchi A, Poma M, Rowley M, Scarpelli R, Laufer R, Gonzalez Paz O, Monteagudo E, Bonelli F, Hazuda D, Stillmock KA, Summa V. Pace P, et al. J Med Chem. 2007 May 3;50(9):2225-39. doi: 10.1021/jm070027u. Epub 2007 Apr 12. J Med Chem. 2007. PMID: 17428043

7

4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors.

Pace P, Spieser SA, Summa V. Pace P, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3865-9. doi: 10.1016/j.bmcl.2008.06.056. Epub 2008 Jun 20. Bioorg Med Chem Lett. 2008. PMID: 18595690

8

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

Summa V, Petrocchi A, Bonelli F, Crescenzi B, Donghi M, Ferrara M, Fiore F, Gardelli C, Gonzalez Paz O, Hazuda DJ, Jones P, Kinzel O, Laufer R, Monteagudo E, Muraglia E, Nizi E, Orvieto F, Pace P, Pescatore G, Scarpelli R, Stillmock K, Witmer MV, Rowley M. Summa V, et al. Among authors: pace p. J Med Chem. 2008 Sep 25;51(18):5843-55. doi: 10.1021/jm800245z. J Med Chem. 2008. PMID: 18763751

9

Novel macrocyclic inhibitors of hepatitis C NS3/4A protease featuring a 2-amino-1,3-thiazole as a P4 carbamate replacement.

Di Francesco ME, Dessole G, Nizi E, Pace P, Koch U, Fiore F, Pesci S, Di Muzio J, Monteagudo E, Rowley M, Summa V. Di Francesco ME, et al. Among authors: pace p. J Med Chem. 2009 Nov 26;52(22):7014-28. doi: 10.1021/jm900524b. J Med Chem. 2009. PMID: 19856919

10

Novel P2-P4 macrocyclic inhibitors of HCV NS3/4A protease by P3 succinamide fragment depeptidization strategy.

Pompei M, Di Francesco ME, Pesci S, Koch U, Vignetti SE, Veneziano M, Pace P, Summa V. Pompei M, et al. Among authors: pace p. Bioorg Med Chem Lett. 2010 Jan 1;20(1):168-74. doi: 10.1016/j.bmcl.2009.11.005. Epub 2009 Nov 10. Bioorg Med Chem Lett. 2010. PMID: 19932966

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

155 results

Search Page

Filters