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Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas.
Lewis R, Li YD, Hoffman L, Hashizume R, Gravohac G, Rice G, Wadhwani NR, Jie C, Pundy T, Mania-Farnell B, Mayanil CS, Soares MB, Lei T, James CD, Foreman NK, Tomita T, Xi G. Lewis R, et al. Among authors: hoffman l. Neoplasia. 2019 Jun;21(6):505-515. doi: 10.1016/j.neo.2019.03.012. Epub 2019 Apr 18. Neoplasia. 2019. PMID: 31005631 Free PMC article.
NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
Griesinger AM, Witt DA, Grob ST, Georgio Westover SR, Donson AM, Sanford B, Mulcahy Levy JM, Wong R, Moreira DC, DeSisto JA, Balakrishnan I, Hoffman LM, Handler MH, Jones KL, Vibhakar R, Venkataraman S, Foreman NK. Griesinger AM, et al. Among authors: hoffman lm. Neuro Oncol. 2017 Oct 1;19(10):1350-1360. doi: 10.1093/neuonc/nox061. Neuro Oncol. 2017. PMID: 28510691 Free PMC article.
Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.
Griesinger AM, Josephson RJ, Donson AM, Mulcahy Levy JM, Amani V, Birks DK, Hoffman LM, Furtek SL, Reigan P, Handler MH, Vibhakar R, Foreman NK. Griesinger AM, et al. Among authors: hoffman lm. Cancer Immunol Res. 2015 Oct;3(10):1165-74. doi: 10.1158/2326-6066.CIR-15-0061. Epub 2015 May 12. Cancer Immunol Res. 2015. PMID: 25968456 Free PMC article.
Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Lake JA, et al. Among authors: hoffman lm. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. doi: 10.1002/pbc.28028. Epub 2019 Oct 8. Pediatr Blood Cancer. 2020. PMID: 31595628 Free PMC article.
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL. DeSisto J, et al. Among authors: hoffman lm. Nat Commun. 2021 Sep 20;12(1):5531. doi: 10.1038/s41467-021-25709-x. Nat Commun. 2021. PMID: 34545084 Free PMC article.
Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Flannery PC, DeSisto JA, Amani V, Venkataraman S, Lemma RT, Prince EW, Donson A, Moroze EE, Hoffman L, Levy JMM, Foreman N, Vibhakar R, Green AL. Flannery PC, et al. Among authors: hoffman l. Oncol Rep. 2018 Feb;39(2):455-464. doi: 10.3892/or.2017.6122. Epub 2017 Nov 29. Oncol Rep. 2018. PMID: 29207163 Free PMC article.
1,500 results