Introduction of a carboxylic acid group into pyrazolylpyridine derivatives increased selectivity for inhibition of the 20-HETE synthase CYP4A11/4F2.
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Bioorg Med Chem. 2023 Oct 18;95:117505. doi: 10.1016/j.bmc.2023.117505. Online ahead of print.
Bioorg Med Chem. 2023.
PMID: 39491277