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A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Singh TD, Song J, Kim J, Chin J, Ji HD, Lee JE, Lee SB, Yoon H, Yu JH, Kim SK, Yoon GS, Hwang H, Lee HW, Oh JM, Lee SW, Lee J, Choi HS, Na SY, Choi WI, Park YJ, Song YS, Kim YA, Lee IK, Cho SJ, Jeon YH. Singh TD, et al. Among authors: cho sj. Clin Cancer Res. 2019 Aug 15;25(16):5069-5081. doi: 10.1158/1078-0432.CCR-18-3007. Epub 2019 Apr 22. Clin Cancer Res. 2019. PMID: 31010838
Identification of Selective ERRγ Inverse Agonists.
Kim J, Im CY, Yoo EK, Ma MJ, Kim SB, Hong E, Chin J, Hwang H, Lee S, Kim ND, Jeon JH, Lee IK, Jeon YH, Choi HS, Kim SH, Cho SJ. Kim J, et al. Among authors: cho sj. Molecules. 2016 Jan 12;21(1):80. doi: 10.3390/molecules21010080. Molecules. 2016. PMID: 26771593 Free PMC article.
Synthesis and biological evaluation of novel 4-hydroxytamoxifen analogs as estrogen-related receptor gamma inverse agonists.
Kim J, Chin J, Im CY, Yoo EK, Woo S, Hwang HJ, Cho JH, Seo KA, Song J, Hwang H, Kim KH, Kim ND, Yoon SK, Jeon JH, Yoon SY, Jeon YH, Choi HS, Lee IK, Kim SH, Cho SJ. Kim J, et al. Among authors: cho sj, cho jh. Eur J Med Chem. 2016 Sep 14;120:338-52. doi: 10.1016/j.ejmech.2016.04.076. Epub 2016 May 9. Eur J Med Chem. 2016. PMID: 27236015
Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Kim J, Woo SY, Im CY, Yoo EK, Lee S, Kim HJ, Hwang HJ, Cho JH, Lee WS, Yoon H, Kim S, Kwon OB, Hwang H, Kim KH, Jeon JH, Singh TD, Kim SW, Hwang SY, Choi HS, Lee IK, Kim SH, Jeon YH, Chin J, Cho SJ. Kim J, et al. Among authors: cho sj, cho jh. J Med Chem. 2016 Nov 23;59(22):10209-10227. doi: 10.1021/acs.jmedchem.6b01204. Epub 2016 Nov 9. J Med Chem. 2016. PMID: 27805390
1,863 results