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Page 1
Intra-islet glucagon signaling is critical for maintaining glucose homeostasis.
Zhu L, Dattaroy D, Pham J, Wang L, Barella LF, Cui Y, Wilkins KJ, Roth BL, Hochgeschwender U, Matschinsky FM, Kaestner KH, Doliba NM, Wess J. Zhu L, et al. Among authors: dattaroy d. JCI Insight. 2019 Apr 23;5(10):e127994. doi: 10.1172/jci.insight.127994. JCI Insight. 2019. PMID: 31012868 Free PMC article.
Allosteric modulation of β-cell M3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice.
Zhu L, Rossi M, Cohen A, Pham J, Zheng H, Dattaroy D, Mukaibo T, Melvin JE, Langel JL, Hattar S, Matschinsky FM, Appella DH, Doliba NM, Wess J. Zhu L, et al. Among authors: dattaroy d. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18684-18690. doi: 10.1073/pnas.1904943116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451647 Free PMC article.
Gq signaling in α cells is critical for maintaining euglycemia.
Liu L, Dattaroy D, Simpson KF, Barella LF, Cui Y, Xiong Y, Jin J, König GM, Kostenis E, Roman JC, Kaestner KH, Doliba NM, Wess J. Liu L, et al. Among authors: dattaroy d. JCI Insight. 2021 Dec 22;6(24):e152852. doi: 10.1172/jci.insight.152852. JCI Insight. 2021. PMID: 34752420 Free PMC article.
Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.
Dattaroy D, Seth RK, Das S, Alhasson F, Chandrashekaran V, Michelotti G, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Dattaroy D, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G510-25. doi: 10.1152/ajpgi.00259.2015. Epub 2015 Dec 30. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26718771 Free PMC article.
M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice.
Seth RK, Das S, Pourhoseini S, Dattaroy D, Igwe S, Ray JB, Fan D, Michelotti GA, Diehl AM, Chatterjee S. Seth RK, et al. Among authors: dattaroy d. J Pharmacol Exp Ther. 2015 Jan;352(1):77-89. doi: 10.1124/jpet.114.218131. Epub 2014 Oct 27. J Pharmacol Exp Ther. 2015. PMID: 25347994 Free PMC article.
Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.
Dattaroy D, Pourhoseini S, Das S, Alhasson F, Seth RK, Nagarkatti M, Michelotti GA, Diehl AM, Chatterjee S. Dattaroy D, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G298-312. doi: 10.1152/ajpgi.00346.2014. Epub 2014 Dec 11. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25501551 Free PMC article.
NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
Das S, Alhasson F, Dattaroy D, Pourhoseini S, Seth RK, Nagarkatti M, Nagarkatti PS, Michelotti GA, Diehl AM, Kalyanaraman B, Chatterjee S. Das S, et al. Among authors: dattaroy d. Am J Pathol. 2015 Jul;185(7):1944-57. doi: 10.1016/j.ajpath.2015.03.024. Epub 2015 May 16. Am J Pathol. 2015. PMID: 25989356 Free PMC article.
18 results