He G - Search Results

1

Design, synthesis and biological evaluation of 4-aniline-thieno[2,3-d]pyrimidine derivatives as MNK1 inhibitors against renal cell carcinoma and nasopharyngeal carcinoma.

Zhang M, Jiang L, Tao J, Pan Z, He M, Su D, He G, Jiang Q. Zhang M, et al. Among authors: he g, he m. Bioorg Med Chem. 2019 Jun 1;27(11):2268-2279. doi: 10.1016/j.bmc.2019.04.022. Epub 2019 Apr 17. Bioorg Med Chem. 2019. PMID: 31014565

2

Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

Luo Y, Ma L, Zheng H, Chen L, Li R, He C, Yang S, Ye X, Chen Z, Li Z, Gao Y, Han J, He G, Yang L, Wei Y. Luo Y, et al. Among authors: he c, he g. J Med Chem. 2010 Jan 14;53(1):273-81. doi: 10.1021/jm901183d. J Med Chem. 2010. PMID: 19904929

3

Selective bone targeting 5-fluorouracil prodrugs: synthesis and preliminary biological evaluation.

Ouyang L, He D, Zhang J, He G, Jiang B, Wang Q, Chen Z, Pan J, Li Y, Guo L. Ouyang L, et al. Among authors: he d, he g. Bioorg Med Chem. 2011 Jun 15;19(12):3750-6. doi: 10.1016/j.bmc.2011.05.004. Epub 2011 May 8. Bioorg Med Chem. 2011. PMID: 21612935

4

Multicomplex-based pharmacophore-guided 3D-QSAR studies of N-substituted 2'-(aminoaryl)benzothiazoles as Aurora-A inhibitors.

He G, Qiu M, Li R, Ouyang L, Wu F, Song X, Cheng L, Xiang M, Yu L. He G, et al. Chem Biol Drug Des. 2012 Jun;79(6):960-71. doi: 10.1111/j.1747-0285.2012.01366.x. Epub 2012 Apr 17. Chem Biol Drug Des. 2012. PMID: 22381081

5

Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives.

Ouyang L, Huang Y, Zhao Y, He G, Xie Y, Liu J, He J, Liu B, Wei Y. Ouyang L, et al. Among authors: he g, he j. Bioorg Med Chem Lett. 2012 May 1;22(9):3044-9. doi: 10.1016/j.bmcl.2012.03.079. Epub 2012 Mar 28. Bioorg Med Chem Lett. 2012. PMID: 22494615

6

[Novel derivatives of diosgenin: design, synthesis and anti-tumor activity].

Ding XY, He G, Jiang HP, Wan JF, Fan JZ. Ding XY, et al. Among authors: he g. Yao Xue Xue Bao. 2012 Apr;47(4):479-85. Yao Xue Xue Bao. 2012. PMID: 22799030 Chinese.

7

Design, synthesis and biological evaluation of enzymatically cleavable NSAIDs prodrugs derived from self-immolative dendritic scaffolds for the treatment of inflammatory diseases.

Wei J, Shi J, Zhang J, He G, Pan J, He J, Zhou R, Guo L, Ouyang L. Wei J, et al. Among authors: he g, he j. Bioorg Med Chem. 2013 Jul 15;21(14):4192-200. doi: 10.1016/j.bmc.2013.05.006. Epub 2013 May 15. Bioorg Med Chem. 2013. PMID: 23719287

8

Novel hybrid virtual screening protocol based on molecular docking and structure-based pharmacophore for discovery of methionyl-tRNA synthetase inhibitors as antibacterial agents.

Liu C, He G, Jiang Q, Han B, Peng C. Liu C, et al. Among authors: he g. Int J Mol Sci. 2013 Jul 9;14(7):14225-39. doi: 10.3390/ijms140714225. Int J Mol Sci. 2013. PMID: 23839093 Free PMC article.

9

Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators with antitumor activity.

Chen C, Wang T, Wu F, Huang W, He G, Ouyang L, Xiang M, Peng C, Jiang Q. Chen C, et al. Among authors: he g. Drug Des Devel Ther. 2014 Sep 2;8:1195-210. doi: 10.2147/DDDT.S62921. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25214764 Free PMC article.

10

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer.

Liu B, Fu L, Zhang C, Zhang L, Zhang Y, Ouyang L, He G, Huang J. Liu B, et al. Among authors: he g. Oncotarget. 2015 Mar 30;6(9):6762-75. doi: 10.18632/oncotarget.3105. Oncotarget. 2015. PMID: 25742792 Free PMC article.

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