Furniss M - Search Results

1

Assessing Drug-Induced Long QT and Proarrhythmic Risk Using Human Stem-Cell-Derived Cardiomyocytes in a Ca2+ Imaging Assay: Evaluation of 28 CiPA Compounds at Three Test Sites.

Lu HR, Zeng H, Kettenhofen R, Guo L, Kopljar I, van Ammel K, Tekle F, Teisman A, Zhai J, Clouse H, Pierson J, Furniss M, Lagrutta A, Sannajust F, Gallacher DJ. Lu HR, et al. Among authors: furniss m. Toxicol Sci. 2019 Aug 1;170(2):345-356. doi: 10.1093/toxsci/kfz102. Toxicol Sci. 2019. PMID: 31020317 Free PMC article.

2

Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment.

Zhang X, Guo L, Zeng H, White SL, Furniss M, Balasubramanian B, Lis E, Lagrutta A, Sannajust F, Zhao LL, Xi B, Wang X, Davis M, Abassi YA. Zhang X, et al. Among authors: furniss m. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:201-16. doi: 10.1016/j.vascn.2016.06.004. Epub 2016 Jun 7. J Pharmacol Toxicol Methods. 2016. PMID: 27282640

3

Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes.

Eldridge S, Guo L, Mussio J, Furniss M, Hamre J 3rd, Davis M. Eldridge S, et al. Among authors: furniss m. Toxicol Sci. 2014 Oct;141(2):547-59. doi: 10.1093/toxsci/kfu150. Epub 2014 Jul 23. Toxicol Sci. 2014. PMID: 25055963 Free PMC article.

4

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways.

Guo L, Eldridge S, Furniss M, Mussio J, Davis M. Guo L, et al. Among authors: furniss m. Curr Protoc Chem Biol. 2015 Sep 1;7(3):141-185. doi: 10.1002/9780470559277.ch150035. Curr Protoc Chem Biol. 2015. PMID: 26331525 Free PMC article.

5

Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro.

Guo L, Eldridge S, Furniss M, Mussio J, Davis M. Guo L, et al. Among authors: furniss m. Toxicol Appl Pharmacol. 2018 Dec 1;360:88-98. doi: 10.1016/j.taap.2018.09.041. Epub 2018 Sep 28. Toxicol Appl Pharmacol. 2018. PMID: 30268579

6

In vitro exposure of precision-cut lung slices to 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole lysylamide dihydrochloride (NSC 710305, Phortress) increases inflammatory cytokine content and tissue damage.

Behrsing HP, Furniss MJ, Davis M, Tomaszewski JE, Parchment RE. Behrsing HP, et al. Among authors: furniss mj. Toxicol Sci. 2013 Feb;131(2):470-9. doi: 10.1093/toxsci/kfs319. Epub 2012 Nov 9. Toxicol Sci. 2013. PMID: 23143926 Free PMC article.

7

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Behrsing HP, Furniss MJ, Robillard KA, Tomaszewski JE, Parchment RE. Behrsing HP, et al. Cancer Chemother Pharmacol. 2010 May;65(6):1083-91. doi: 10.1007/s00280-009-1113-7. Epub 2009 Aug 29. Cancer Chemother Pharmacol. 2010. PMID: 19727731 Free PMC article.

8

Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms.

Brill SS, Furimsky AM, Ho MN, Furniss MJ, Li Y, Green AG, Bradford WW, Green CE, Kapetanovic IM, Iyer LV. Brill SS, et al. Among authors: furniss mj. J Pharm Pharmacol. 2006 Apr;58(4):469-79. doi: 10.1211/jpp.58.4.0006. J Pharm Pharmacol. 2006. PMID: 16597364

9

Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models.

Ray S, Madrid PB, Catz P, LeValley SE, Furniss MJ, Rausch LL, Guy RK, DeRisi JL, Iyer LV, Green CE, Mirsalis JC. Ray S, et al. J Med Chem. 2010 May 13;53(9):3685-95. doi: 10.1021/jm100057h. J Med Chem. 2010. PMID: 20361799 Free PMC article.

10

Dual activity of pyrrolidine dithiocarbamate on kappaB-dependent gene expression in U937 cells: II. Regulation by tumour necrosis factor-alpha.

Watanabe K, Kazakova I, Furniss M, Miller SC. Watanabe K, et al. Among authors: furniss m. Cell Signal. 1999 May;11(5):371-83. doi: 10.1016/s0898-6568(99)00022-4. Cell Signal. 1999. PMID: 10376811

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