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Phenotypic screening of the 'Kurz-box' of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus.
Nguyen LT, Kurz T, Preston S, Brueckmann H, Lungerich B, Herath HMPD, Koehler AV, Wang T, Skálová L, Jabbar A, Gasser RB. Nguyen LT, et al. Among authors: preston s. Parasit Vectors. 2019 Apr 30;12(1):191. doi: 10.1186/s13071-019-3426-7. Parasit Vectors. 2019. PMID: 31039802 Free PMC article.
Low cost whole-organism screening of compounds for anthelmintic activity.
Preston S, Jabbar A, Nowell C, Joachim A, Ruttkowski B, Baell J, Cardno T, Korhonen PK, Piedrafita D, Ansell BR, Jex AR, Hofmann A, Gasser RB. Preston S, et al. Int J Parasitol. 2015 Apr;45(5):333-43. doi: 10.1016/j.ijpara.2015.01.007. Epub 2015 Mar 5. Int J Parasitol. 2015. PMID: 25746136
A practical Java tool for small-molecule compound appraisal.
Amani P, Sneyd T, Preston S, Young ND, Mason L, Bailey UM, Baell J, Camp D, Gasser RB, Gorse AD, Taylor P, Hofmann A. Amani P, et al. Among authors: preston s. J Cheminform. 2015 Jun 16;7:28. doi: 10.1186/s13321-015-0079-1. eCollection 2015. J Cheminform. 2015. PMID: 26082805 Free PMC article.
Metabolic profiling and in vitro assessment of anthelmintic fractions of Picria fel-terrae Lour.
Kumarasingha R, Karpe AV, Preston S, Yeo TC, Lim DSL, Tu CL, Luu J, Simpson KJ, Shaw JM, Gasser RB, Beale DJ, Morrison PD, Palombo EA, Boag PR. Kumarasingha R, et al. Among authors: preston s. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):171-178. doi: 10.1016/j.ijpddr.2016.08.002. Epub 2016 Aug 26. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27639945 Free PMC article.
856 results