Le T - Search Results

1

The FOXM1 Inhibitor RCM-1 Decreases Carcinogenesis and Nuclear β-Catenin.

Shukla S, Milewski D, Pradhan A, Rama N, Rice K, Le T, Flick MJ, Vaz S, Zhao X, Setchell KD, Logarinho E, Kalinichenko VV, Kalin TV. Shukla S, et al. Among authors: le t. Mol Cancer Ther. 2019 Jul;18(7):1217-1229. doi: 10.1158/1535-7163.MCT-18-0709. Epub 2019 Apr 30. Mol Cancer Ther. 2019. PMID: 31040162 Free PMC article.

2

SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.

Cheng XH, Black M, Ustiyan V, Le T, Fulford L, Sridharan A, Medvedovic M, Kalinichenko VV, Whitsett JA, Kalin TV. Cheng XH, et al. Among authors: le t. PLoS Genet. 2014 Sep 25;10(9):e1004656. doi: 10.1371/journal.pgen.1004656. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25254494 Free PMC article.

3

FOXF1 maintains endothelial barrier function and prevents edema after lung injury.

Cai Y, Bolte C, Le T, Goda C, Xu Y, Kalin TV, Kalinichenko VV. Cai Y, et al. Among authors: le t. Sci Signal. 2016 Apr 19;9(424):ra40. doi: 10.1126/scisignal.aad1899. Sci Signal. 2016. PMID: 27095594

4

The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.

Fulford L, Milewski D, Ustiyan V, Ravishankar N, Cai Y, Le T, Masineni S, Kasper S, Aronow B, Kalinichenko VV, Kalin TV. Fulford L, et al. Among authors: le t. Sci Signal. 2016 May 10;9(427):ra48. doi: 10.1126/scisignal.aad5582. Sci Signal. 2016. PMID: 27165781

5

FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21^Cip1 CDK inhibitor.

Milewski D, Pradhan A, Wang X, Cai Y, Le T, Turpin B, Kalinichenko VV, Kalin TV. Milewski D, et al. Among authors: le t. Oncogene. 2017 Feb 9;36(6):850-862. doi: 10.1038/onc.2016.254. Epub 2016 Jul 18. Oncogene. 2017. PMID: 27425595 Free PMC article.

6

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

Milewski D, Balli D, Ustiyan V, Le T, Dienemann H, Warth A, Breuhahn K, Whitsett JA, Kalinichenko VV, Kalin TV. Milewski D, et al. Among authors: le t. PLoS Genet. 2017 Dec 21;13(12):e1007097. doi: 10.1371/journal.pgen.1007097. eCollection 2017 Dec. PLoS Genet. 2017. PMID: 29267283 Free PMC article.

7

FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts.

Black M, Milewski D, Le T, Ren X, Xu Y, Kalinichenko VV, Kalin TV. Black M, et al. Among authors: le t. Cell Rep. 2018 Apr 10;23(2):442-458. doi: 10.1016/j.celrep.2018.03.067. Cell Rep. 2018. PMID: 29642003 Free PMC article.

8

Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway.

Goda C, Balli D, Black M, Milewski D, Le T, Ustiyan V, Ren X, Kalinichenko VV, Kalin TV. Goda C, et al. Among authors: le t. PLoS Genet. 2020 Apr 9;16(4):e1008692. doi: 10.1371/journal.pgen.1008692. eCollection 2020 Apr. PLoS Genet. 2020. PMID: 32271749 Free PMC article.

9

Lung endothelial cells regulate pulmonary fibrosis through FOXF1/R-Ras signaling.

Bian F, Lan YW, Zhao S, Deng Z, Shukla S, Acharya A, Donovan J, Le T, Milewski D, Bacchetta M, Hozain AE, Tipograf Y, Chen YW, Xu Y, Shi D, Kalinichenko VV, Kalin TV. Bian F, et al. Among authors: le t. Nat Commun. 2023 May 4;14(1):2560. doi: 10.1038/s41467-023-38177-2. Nat Commun. 2023. PMID: 37137915 Free PMC article.

10

Ultra-high dose-rate proton FLASH improves tumor control.

Shukla S, Saha T, Rama N, Acharya A, Le T, Bian F, Donovan J, Tan LA, Vatner R, Kalinichenko V, Mascia A, Perentesis JP, Kalin TV. Shukla S, et al. Among authors: le t. Radiother Oncol. 2023 Sep;186:109741. doi: 10.1016/j.radonc.2023.109741. Epub 2023 Jun 12. Radiother Oncol. 2023. PMID: 37315577 Free PMC article.

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