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Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma.
Cao D, Lei Y, Ye Z, Zhao L, Wang H, Zhang J, He F, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Wagstaff W, Zhao X, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, He TC, Liao Z. Cao D, et al. Among authors: pakvasa m. Am J Cancer Res. 2020 Oct 1;10(10):3248-3266. eCollection 2020. Am J Cancer Res. 2020. PMID: 33163268 Free PMC article.
The inhibition of BRAF activity sensitizes chemoresistant human ovarian cancer cells to paclitaxel-induced cytotoxicity and tumor growth inhibition.
Zhao L, Huang L, Zhang J, Fan J, He F, Zhao X, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Pakvasa M, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, Qi H, He TC. Zhao L, et al. Among authors: pakvasa m. Am J Transl Res. 2020 Dec 15;12(12):8084-8098. eCollection 2020. Am J Transl Res. 2020. PMID: 33437383 Free PMC article.
A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs).
Zhao X, Huang B, Wang H, Ni N, He F, Liu Q, Shi D, Chen C, Zhao P, Wang X, Wagstaff W, Pakvasa M, Tucker AB, Lee MJ, Wolf JM, Reid RR, Hynes K, Strelzow J, Ho SH, Yu T, Yang J, Shen L, He TC, Zhang Y. Zhao X, et al. Among authors: pakvasa m. Am J Transl Res. 2021 May 15;13(5):4233-4250. eCollection 2021. Am J Transl Res. 2021. PMID: 34150011 Free PMC article.
lncRNA Rmst acts as an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by antagonizing Notch-targeting microRNAs.
Zhang Z, Liu J, Zeng Z, Fan J, Huang S, Zhang L, Zhang B, Wang X, Feng Y, Ye Z, Zhao L, Cao D, Yang L, Pakvasa M, Liu B, Wagstaff W, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Ding H, Zhang Y, Niu C, Haydon RC, Luu HH, Lee MJ, Wolf JM, Shao Z, He TC. Zhang Z, et al. Among authors: pakvasa m. Aging (Albany NY). 2019 Dec 11;11(24):12476-12496. doi: 10.18632/aging.102583. Epub 2019 Dec 11. Aging (Albany NY). 2019. PMID: 31825894 Free PMC article.
SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine.
Huang X, Chen Q, Luo W, Pakvasa M, Zhang Y, Zheng L, Li S, Yang Z, Zeng H, Liang F, Zhang F, Hu DA, Qin KH, Wang EJ, Qin DS, Reid RR, He TC, Athiviraham A, El Dafrawy M, Zhang H. Huang X, et al. Among authors: pakvasa m. Genes Dis. 2020 Oct 17;9(1):95-107. doi: 10.1016/j.gendis.2020.10.003. eCollection 2022 Jan. Genes Dis. 2020. PMID: 35005110 Free PMC article. Review.
The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine.
Mostafa S, Pakvasa M, Coalson E, Zhu A, Alverdy A, Castillo H, Fan J, Li A, Feng Y, Wu D, Bishop E, Du S, Spezia M, Li A, Hagag O, Deng A, Liu W, Li M, Ho SS, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, Luu HH, Haydon RC, Strelzow J, Hynes K, He TC, Reid RR. Mostafa S, et al. Among authors: pakvasa m. Genes Dis. 2019 Jul 24;6(3):201-223. doi: 10.1016/j.gendis.2019.07.003. eCollection 2019 Sep. Genes Dis. 2019. PMID: 32042861 Free PMC article. Review.
Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism.
Liu W, Deng Z, Zeng Z, Fan J, Feng Y, Wang X, Cao D, Zhang B, Yang L, Liu B, Pakvasa M, Wagstaff W, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Ding H, Zhang Y, Niu C, Haydon RC, Luu HH, Wolf JM, Lee MJ, Huang W, He TC, Zou Y. Liu W, et al. Among authors: pakvasa m. Genes Dis. 2019 Sep 14;7(2):235-244. doi: 10.1016/j.gendis.2019.08.003. eCollection 2020 Jun. Genes Dis. 2019. PMID: 32215293 Free PMC article.
36 results