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MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.
Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, Adams DJ, Saez-Rodriguez J, Smith PD, Cook SJ. Sale MJ, et al. Among authors: saxena j. Nat Commun. 2019 May 2;10(1):2030. doi: 10.1038/s41467-019-09438-w. Nat Commun. 2019. PMID: 31048689 Free PMC article.
A novel cell line panel reveals non-genetic mediators of platinum resistance and phenotypic diversity in high grade serous ovarian cancer.
Hoare JI, Hockings H, Saxena J, Silva VL, Haughey MJ, Wood GE, Nicolini F, Mirza H, McNeish IA, Huang W, Maniati E, Graham TA, Lockley M. Hoare JI, et al. Among authors: saxena j. Gynecol Oncol. 2022 Oct;167(1):96-106. doi: 10.1016/j.ygyno.2022.07.027. Epub 2022 Jul 30. Gynecol Oncol. 2022. PMID: 35918200 Free article.
Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells.
Bartesaghi S, Graziano V, Galavotti S, Henriquez NV, Betts J, Saxena J, Minieri V, A D, Karlsson A, Martins LM, Capasso M, Nicotera P, Brandner S, De Laurenzi V, Salomoni P. Bartesaghi S, et al. Among authors: saxena j. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1059-64. doi: 10.1073/pnas.1413165112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583481 Free PMC article.
Probiotic Lactobacillus salivarius mediated synthesis of silver nanoparticles (AgNPs-LS): A sustainable approach and multifaceted biomedical application.
Abdelgadir A, Adnan M, Patel M, Saxena J, Alam MJ, Alshahrani MM, Singh R, Sachidanandan M, Badraoui R, Siddiqui AJ. Abdelgadir A, et al. Among authors: saxena j. Heliyon. 2024 Sep 17;10(18):e37987. doi: 10.1016/j.heliyon.2024.e37987. eCollection 2024 Sep 30. Heliyon. 2024. PMID: 39347420 Free PMC article.
Biomarkers in sepsis.
Saxena J, Das S, Kumar A, Sharma A, Sharma L, Kaushik S, Kumar Srivastava V, Jamal Siddiqui A, Jyoti A. Saxena J, et al. Clin Chim Acta. 2024 Aug 15;562:119891. doi: 10.1016/j.cca.2024.119891. Epub 2024 Jul 26. Clin Chim Acta. 2024. PMID: 39067500 Review.
216 results