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Page 1
Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation.
Ando H, Sato T, Ito T, Yamamoto J, Sakamoto S, Nitta N, Asatsuma-Okumura T, Shimizu N, Mizushima R, Aoki I, Imai T, Yamaguchi Y, Berk AJ, Handa H. Ando H, et al. Among authors: asatsuma okumura t. iScience. 2019 May 31;15:95-108. doi: 10.1016/j.isci.2019.04.007. Epub 2019 Apr 9. iScience. 2019. PMID: 31055217 Free PMC article.
Molecular mechanisms of cereblon-based drugs.
Asatsuma-Okumura T, Ito T, Handa H. Asatsuma-Okumura T, et al. Pharmacol Ther. 2019 Oct;202:132-139. doi: 10.1016/j.pharmthera.2019.06.004. Epub 2019 Jun 14. Pharmacol Ther. 2019. PMID: 31202702 Review.
p63 is a cereblon substrate involved in thalidomide teratogenicity.
Asatsuma-Okumura T, Ando H, De Simone M, Yamamoto J, Sato T, Shimizu N, Asakawa K, Yamaguchi Y, Ito T, Guerrini L, Handa H. Asatsuma-Okumura T, et al. Nat Chem Biol. 2019 Nov;15(11):1077-1084. doi: 10.1038/s41589-019-0366-7. Epub 2019 Oct 7. Nat Chem Biol. 2019. PMID: 31591562
ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells.
Yamamoto J, Suwa T, Murase Y, Tateno S, Mizutome H, Asatsuma-Okumura T, Shimizu N, Kishi T, Momose S, Kizaki M, Ito T, Yamaguchi Y, Handa H. Yamamoto J, et al. Among authors: asatsuma okumura t. Nat Chem Biol. 2020 Nov;16(11):1208-1217. doi: 10.1038/s41589-020-0645-3. Epub 2020 Sep 21. Nat Chem Biol. 2020. PMID: 32958952
Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.
Kashiwada T, Takano R, Ando F, Kuroda S, Miyabe Y, Owada R, Miyanaga A, Asatsuma-Okumura T, Hashiguchi M, Kanazawa Y, Yoshida H, Seike M, Gemma A, Iwai Y. Kashiwada T, et al. Among authors: asatsuma okumura t. Front Pharmacol. 2024 May 10;15:1384733. doi: 10.3389/fphar.2024.1384733. eCollection 2024. Front Pharmacol. 2024. PMID: 38799168 Free PMC article.
Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cancer.
Ando F, Kashiwada T, Kuroda S, Fujii T, Takano R, Miyabe Y, Kunugi S, Sakatani T, Miyanaga A, Asatsuma-Okumura T, Hashiguchi M, Kanazawa Y, Ohashi R, Yoshida H, Seike M, Gemma A, Iwai Y. Ando F, et al. Among authors: asatsuma okumura t. Front Pharmacol. 2024 May 7;15:1384731. doi: 10.3389/fphar.2024.1384731. eCollection 2024. Front Pharmacol. 2024. PMID: 38774209 Free PMC article.