Schulga A - Search Results

1

Penetration Efficiency of Antitumor Agents in Ovarian Cancer Spheroids: The Case of Recombinant Targeted Toxin DARPin-LoPE and the Chemotherapy Drug, Doxorubicin.

Sokolova E, Kutova O, Grishina A, Pospelov A, Guryev E, Schulga A, Deyev S, Balalaeva I. Sokolova E, et al. Among authors: schulga a. Pharmaceutics. 2019 May 7;11(5):219. doi: 10.3390/pharmaceutics11050219. Pharmaceutics. 2019. PMID: 31067739 Free PMC article.

2

Recombinant targeted toxin based on HER2-specific DARPin possesses a strong selective cytotoxic effect in vitro and a potent antitumor activity in vivo.

Sokolova E, Proshkina G, Kutova O, Shilova O, Ryabova A, Schulga A, Stremovskiy O, Zdobnova T, Balalaeva I, Deyev S. Sokolova E, et al. Among authors: schulga a. J Control Release. 2016 Jul 10;233:48-56. doi: 10.1016/j.jconrel.2016.05.020. Epub 2016 May 10. J Control Release. 2016. PMID: 27178808

3

Data on characterization of magnetic nanoparticles stabilized with fusion protein of Barstar and C-term part of Mms6.

Shipunova VO, Kotelnikova PA, Aghayeva UF, Stremovskiy OA, Schulga AA, Nikitin MP, Deyev SM. Shipunova VO, et al. Among authors: schulga aa. Data Brief. 2018 Nov 3;21:1659-1663. doi: 10.1016/j.dib.2018.10.173. eCollection 2018 Dec. Data Brief. 2018. PMID: 30505896 Free PMC article.

4

Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties.

Deyev S, Vorobyeva A, Schulga A, Proshkina G, Güler R, Löfblom J, Mitran B, Garousi J, Altai M, Buijs J, Chernov V, Orlova A, Tolmachev V. Deyev S, et al. Among authors: schulga a. Mol Pharm. 2019 Mar 4;16(3):995-1008. doi: 10.1021/acs.molpharmaceut.8b00922. Epub 2019 Feb 8. Mol Pharm. 2019. PMID: 30608701

5

HER2-Specific Targeted Toxin DARPin-LoPE: Immunogenicity and Antitumor Effect on Intraperitoneal Ovarian Cancer Xenograft Model.

Sokolova EA, Shilova ON, Kiseleva DV, Schulga AA, Balalaeva IV, Deyev SM. Sokolova EA, et al. Among authors: schulga aa. Int J Mol Sci. 2019 May 15;20(10):2399. doi: 10.3390/ijms20102399. Int J Mol Sci. 2019. PMID: 31096563 Free PMC article.

6

Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging.

Vorobyeva A, Schulga A, Rinne SS, Günther T, Orlova A, Deyev S, Tolmachev V. Vorobyeva A, et al. Among authors: schulga a. Int J Mol Sci. 2019 Jun 21;20(12):3047. doi: 10.3390/ijms20123047. Int J Mol Sci. 2019. PMID: 31234471 Free PMC article.

7

Optimal composition and position of histidine-containing tags improves biodistribution of ^99mTc-labeled DARPin G3.

Vorobyeva A, Schulga A, Konovalova E, Güler R, Löfblom J, Sandström M, Garousi J, Chernov V, Bragina O, Orlova A, Tolmachev V, Deyev SM. Vorobyeva A, et al. Among authors: schulga a. Sci Rep. 2019 Jun 28;9(1):9405. doi: 10.1038/s41598-019-45795-8. Sci Rep. 2019. PMID: 31253840 Free PMC article.

8

Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.

Deyev SM, Vorobyeva A, Schulga A, Abouzayed A, Günther T, Garousi J, Konovalova E, Ding H, Gräslund T, Orlova A, Tolmachev V. Deyev SM, et al. Among authors: schulga a. Int J Biol Macromol. 2020 Feb 15;145:216-225. doi: 10.1016/j.ijbiomac.2019.12.147. Epub 2019 Dec 19. Int J Biol Macromol. 2020. PMID: 31863835 Free article.

9

On the prevention of kidney uptake of radiolabeled DARPins.

Altai M, Garousi J, Rinne SS, Schulga A, Deyev S, Vorobyeva A. Altai M, et al. Among authors: schulga a. EJNMMI Res. 2020 Feb 4;10(1):7. doi: 10.1186/s13550-020-0599-1. EJNMMI Res. 2020. PMID: 32020413 Free PMC article.

10

Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1.

Vorobyeva A, Konovalova E, Xu T, Schulga A, Altai M, Garousi J, Rinne SS, Orlova A, Tolmachev V, Deyev S. Vorobyeva A, et al. Among authors: schulga a. Int J Mol Sci. 2020 May 7;21(9):3310. doi: 10.3390/ijms21093310. Int J Mol Sci. 2020. PMID: 32392820 Free PMC article.

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