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IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.
Zumaquero E, Stone SL, Scharer CD, Jenks SA, Nellore A, Mousseau B, Rosal-Vela A, Botta D, Bradley JE, Wojciechowski W, Ptacek T, Danila MI, Edberg JC, Bridges SL Jr, Kimberly RP, Chatham WW, Schoeb TR, Rosenberg AF, Boss JM, Sanz I, Lund FE. Zumaquero E, et al. Among authors: jenks sa. Elife. 2019 May 15;8:e41641. doi: 10.7554/eLife.41641. Elife. 2019. PMID: 31090539 Free PMC article.
Protein kinase Cβ is required for lupus development in Sle mice.
Oleksyn D, Pulvino M, Zhao J, Misra R, Vosoughi A, Jenks S, Tipton C, Lund F, Schwartz G, Goldman B, Mohan C, Mehta K, Mehta M, Leitgets M, Sanz I, Chen L. Oleksyn D, et al. Arthritis Rheum. 2013 Apr;65(4):1022-31. doi: 10.1002/art.37825. Arthritis Rheum. 2013. PMID: 23280626 Free PMC article.
Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus.
Richardson C, Chida AS, Adlowitz D, Silver L, Fox E, Jenks SA, Palmer E, Wang Y, Heimburg-Molinaro J, Li QZ, Mohan C, Cummings R, Tipton C, Sanz I. Richardson C, et al. Among authors: jenks sa. J Immunol. 2013 Nov 15;191(10):4926-39. doi: 10.4049/jimmunol.1202263. Epub 2013 Oct 9. J Immunol. 2013. PMID: 24108696 Free PMC article.
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Lee FE, Boss JM, Lund FE, Sanz I. Jenks SA, et al. Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9. Immunity. 2018. PMID: 30314758 Free PMC article.
Extrafollicular responses in humans and SLE.
Jenks SA, Cashman KS, Woodruff MC, Lee FE, Sanz I. Jenks SA, et al. Immunol Rev. 2019 Mar;288(1):136-148. doi: 10.1111/imr.12741. Immunol Rev. 2019. PMID: 30874345 Free PMC article. Review.
Epigenetic programming underpins B cell dysfunction in human SLE.
Scharer CD, Blalock EL, Mi T, Barwick BG, Jenks SA, Deguchi T, Cashman KS, Neary BE, Patterson DG, Hicks SL, Khosroshahi A, Eun-Hyung Lee F, Wei C, Sanz I, Boss JM. Scharer CD, et al. Among authors: jenks sa. Nat Immunol. 2019 Aug;20(8):1071-1082. doi: 10.1038/s41590-019-0419-9. Epub 2019 Jul 1. Nat Immunol. 2019. PMID: 31263277 Free PMC article.
38 results