Smith LM - Search Results

1

In Vivo Synaptic Density Imaging with ¹¹C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease.

Toyonaga T, Smith LM, Finnema SJ, Gallezot JD, Naganawa M, Bini J, Mulnix T, Cai Z, Ropchan J, Huang Y, Strittmatter SM, Carson RE. Toyonaga T, et al. Among authors: smith lm. J Nucl Med. 2019 Dec;60(12):1780-1786. doi: 10.2967/jnumed.118.223867. Epub 2019 May 17. J Nucl Med. 2019. PMID: 31101744 Free PMC article.

2

Binding Sites for Amyloid-β Oligomers and Synaptic Toxicity.

Smith LM, Strittmatter SM. Smith LM, et al. Cold Spring Harb Perspect Med. 2017 May 1;7(5):a024075. doi: 10.1101/cshperspect.a024075. Cold Spring Harb Perspect Med. 2017. PMID: 27940601 Free PMC article. Review.

3

Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.

Haas LT, Salazar SV, Smith LM, Zhao HR, Cox TO, Herber CS, Degnan AP, Balakrishnan A, Macor JE, Albright CF, Strittmatter SM. Haas LT, et al. Among authors: smith lm. Cell Rep. 2017 Jul 5;20(1):76-88. doi: 10.1016/j.celrep.2017.06.023. Cell Rep. 2017. PMID: 28683325 Free PMC article.

4

Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model.

Smith LM, Zhu R, Strittmatter SM. Smith LM, et al. Neuropharmacology. 2018 Mar 1;130:54-61. doi: 10.1016/j.neuropharm.2017.11.042. Epub 2017 Nov 27. Neuropharmacology. 2018. PMID: 29191754 Free PMC article.

5

Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists.

Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, Schneekloth JS, Merkel J, Teran C, Naderi ZK, Supattapone S, Strittmatter SM. Gunther EC, et al. Among authors: smith lm. Cell Rep. 2019 Jan 2;26(1):145-158.e8. doi: 10.1016/j.celrep.2018.12.021. Cell Rep. 2019. PMID: 30605671 Free PMC article.

6

Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance.

Smith LM, Kostylev MA, Lee S, Strittmatter SM. Smith LM, et al. J Biol Chem. 2019 Apr 12;294(15):6042-6053. doi: 10.1074/jbc.RA118.006252. Epub 2019 Feb 20. J Biol Chem. 2019. PMID: 30787106 Free PMC article.

7

Anti-PrP^C antibody rescues cognition and synapses in transgenic alzheimer mice.

Cox TO, Gunther EC, Brody AH, Chiasseu MT, Stoner A, Smith LM, Haas LT, Hammersley J, Rees G, Dosanjh B, Groves M, Gardener M, Dobson C, Vaughan T, Chessell I, Billinton A, Strittmatter SM. Cox TO, et al. Among authors: smith lm. Ann Clin Transl Neurol. 2019 Feb 27;6(3):554-574. doi: 10.1002/acn3.730. eCollection 2019 Mar. Ann Clin Transl Neurol. 2019. PMID: 30911579 Free PMC article.

8

Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy.

Tang SJ, Fesharaki-Zadeh A, Takahashi H, Nies SH, Smith LM, Luo A, Chyung A, Chiasseu M, Strittmatter SM. Tang SJ, et al. Among authors: smith lm. Acta Neuropathol Commun. 2020 Jul 1;8(1):96. doi: 10.1186/s40478-020-00976-9. Acta Neuropathol Commun. 2020. PMID: 32611392 Free PMC article.

9

Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.

Brody AH, Nies SH, Guan F, Smith LM, Mukherjee B, Salazar SA, Lee S, Lam TKT, Strittmatter SM. Brody AH, et al. Among authors: smith lm. Mol Neurodegener. 2022 May 3;17(1):32. doi: 10.1186/s13024-022-00526-y. Mol Neurodegener. 2022. PMID: 35501917 Free PMC article.

10

Correction: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.

Brody AH, Nies SH, Guan F, Smith LM, Mukherjee B, Salazar SA, Lee S, Lam TKT, Strittmatter SM. Brody AH, et al. Among authors: smith lm. Mol Neurodegener. 2022 Aug 30;17(1):56. doi: 10.1186/s13024-022-00557-5. Mol Neurodegener. 2022. PMID: 36038879 Free PMC article. No abstract available.

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