Lu XJ - Search Results

1

Non-transition Metal-Mediated Diverse Aryl-Heteroatom Bond Formation of Arylammonium Salts.

Wang DY, Wen X, Xiong CD, Zhao JN, Ding CY, Meng Q, Zhou H, Wang C, Uchiyama M, Lu XJ, Zhang A. Wang DY, et al. Among authors: lu xj. iScience. 2019 May 31;15:307-315. doi: 10.1016/j.isci.2019.04.038. Epub 2019 May 3. iScience. 2019. PMID: 31102996 Free PMC article.

2

Ruthenium-Promoted C-H Activation Reactions between DNA-Conjugated Acrylamide and Aromatic Acids.

Wang X, Sun H, Liu J, Dai D, Zhang M, Zhou H, Zhong W, Lu X. Wang X, et al. Org Lett. 2018 Aug 17;20(16):4764-4768. doi: 10.1021/acs.orglett.8b01837. Epub 2018 Aug 6. Org Lett. 2018. PMID: 30080052

3

Palladium-Promoted DNA-Compatible Heck Reaction.

Wang X, Sun H, Liu J, Zhong W, Zhang M, Zhou H, Dai D, Lu X. Wang X, et al. Org Lett. 2019 Feb 1;21(3):719-723. doi: 10.1021/acs.orglett.8b03926. Epub 2019 Jan 24. Org Lett. 2019. PMID: 30676761

4

Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering.

Li K, Liu X, Liu S, An Y, Shen Y, Sun Q, Shi X, Su W, Cui W, Duan Z, Kuai L, Yang H, Satz AL, Chen K, Jiang H, Zheng M, Peng X, Lu X. Li K, et al. iScience. 2020 Jun 26;23(6):101142. doi: 10.1016/j.isci.2020.101142. Epub 2020 May 7. iScience. 2020. PMID: 32446221 Free PMC article.

5

On-DNA Cross-Dehydrogenative Coupling Reaction toward the Synthesis of Focused DNA-Encoded Tetrahydroisoquinoline Libraries.

Wen X, Duan Z, Liu J, Lu W, Lu X. Wen X, et al. Org Lett. 2020 Aug 7;22(15):5721-5725. doi: 10.1021/acs.orglett.0c01565. Epub 2020 Jul 9. Org Lett. 2020. PMID: 32644810

6

Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins.

Li L, Su M, Lu W, Song H, Liu J, Wen X, Suo Y, Qi J, Luo X, Zhou YB, Liao XH, Li J, Lu X. Li L, et al. ACS Med Chem Lett. 2022 Aug 15;13(10):1574-1581. doi: 10.1021/acsmedchemlett.2c00127. eCollection 2022 Oct 13. ACS Med Chem Lett. 2022. PMID: 36262386 Free PMC article.

7

Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization.

Wen X, Wu X, Jin R, Lu X. Wen X, et al. Eur J Med Chem. 2023 Feb 15;248:115079. doi: 10.1016/j.ejmech.2022.115079. Epub 2023 Jan 14. Eur J Med Chem. 2023. PMID: 36669370 Review.

8

Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library.

Wen X, Zhang M, Duan Z, Suo Y, Lu W, Jin R, Mu B, Li K, Zhang X, Meng L, Hong Y, Wang X, Hu H, Zhu J, Song W, Shen A, Lu X. Wen X, et al. J Med Chem. 2023 Aug 24;66(16):11118-11132. doi: 10.1021/acs.jmedchem.2c02129. Epub 2023 Aug 8. J Med Chem. 2023. PMID: 37552553

9

ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries.

Jiang L, Liu S, Jia X, Gong Q, Wen X, Lu W, Yang J, Wu X, Wang X, Suo Y, Li Y, Uesugi M, Qu ZB, Tan M, Lu X, Zhou L. Jiang L, et al. J Am Chem Soc. 2023 Nov 22;145(46):25283-25292. doi: 10.1021/jacs.3c08852. Epub 2023 Oct 19. J Am Chem Soc. 2023. PMID: 37857329

10

Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach.

Qin S, Feng L, Zhao Q, Yan Z, Lyu X, Li K, Mu B, Chen Y, Lu W, Wang C, Suo Y, Yue J, Cui M, Li Y, Zhao Y, Duan Z, Zhu J, Lu X. Qin S, et al. J Med Chem. 2024 Jan 25;67(2):1079-1092. doi: 10.1021/acs.jmedchem.3c01463. Epub 2024 Jan 3. J Med Chem. 2024. PMID: 38166388

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