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Zeb2 drives invasive and microbiota-dependent colon carcinoma.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, Vikkula H, Radaelli E, Haigh JJ, Jonckheere S, Taminau J, Vandamme N, Wullaert A, Tulchinsky E, Nittner D, Van Vlierberghe P, De Hertogh G, Baldin P, Etlioglu E, Wirapati P, Boon L, Lambrecht BN, Callewaert C, Tejpar S, Goossens S, Berx G, Vereecke L, van Loo G. Slowicka K, et al. Among authors: haigh jj. Nat Cancer. 2020 Jun;1(6):620-634. doi: 10.1038/s43018-020-0070-2. Epub 2020 Jun 15. Nat Cancer. 2020. PMID: 35121975
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.
Goossens S, Wang J, Tremblay CS, De Medts J, T'Sas S, Nguyen T, Saw J, Haigh K, Curtis DJ, Van Vlierberghe P, Berx G, Taghon T, Haigh JJ. Goossens S, et al. Among authors: haigh jj, haigh k. Haematologica. 2019 Aug;104(8):1608-1616. doi: 10.3324/haematol.2018.207837. Epub 2019 Jan 24. Haematologica. 2019. PMID: 30679322 Free PMC article.
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.
Carmichael CL, Wang J, Nguyen T, Kolawole O, Benyoucef A, De Mazière C, Milne AR, Samuel S, Gillinder K, Hediyeh-Zadeh S, Vo ANQ, Huang Y, Knezevic K, McInnes WRL, Shields BJ, Mitchell H, Ritchie ME, Lammens T, Lintermans B, Van Vlierberghe P, Wong NC, Haigh K, Thoms JAI, Toulmin E, Curtis DJ, Oxley EP, Dickins RA, Beck D, Perkins A, McCormack MP, Davis MJ, Berx G, Zuber J, Pimanda JE, Kile BT, Goossens S, Haigh JJ. Carmichael CL, et al. Among authors: haigh jj, haigh k. Blood. 2020 Aug 20;136(8):957-973. doi: 10.1182/blood.2019002548. Blood. 2020. PMID: 32369597 Free PMC article.
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Wang J, Farkas C, Benyoucef A, Carmichael C, Haigh K, Wong N, Huylebroeck D, Stemmler MP, Brabletz S, Brabletz T, Nefzger CM, Goossens S, Berx G, Polo JM, Haigh JJ. Wang J, et al. Among authors: haigh jj, haigh k. PLoS Biol. 2021 Sep 22;19(9):e3001394. doi: 10.1371/journal.pbio.3001394. eCollection 2021 Sep. PLoS Biol. 2021. PMID: 34550965 Free PMC article.
99 results