Frydenvang K - Search Results

1

Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.

Giraudo A, Krall J, Bavo F, Nielsen B, Kongstad KT, Rolando B, De Blasio R, Gloriam DE, Löffler R, Thiesen L, Harpsøe K, Frydenvang K, Boschi D, Wellendorph P, Lolli ML, Jensen AA, Frølund B. Giraudo A, et al. Among authors: frydenvang k. J Med Chem. 2019 Jun 27;62(12):5797-5809. doi: 10.1021/acs.jmedchem.9b00026. Epub 2019 Jun 5. J Med Chem. 2019. PMID: 31117514 Free article.

2

Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.

Johansen TN, Frydenvang K, Ebert B, Krogsgaard-Larsen P, Madsen U. Johansen TN, et al. Among authors: frydenvang k. J Med Chem. 1994 Sep 30;37(20):3252-62. doi: 10.1021/jm00046a009. J Med Chem. 1994. PMID: 7523673

3

N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.

Madsen U, Frydenvang K, Ebert B, Johansen TN, Brehm L, Krogsgaard-Larsen P. Madsen U, et al. Among authors: frydenvang k. J Med Chem. 1996 Jan 5;39(1):183-90. doi: 10.1021/jm950393q. J Med Chem. 1996. PMID: 8568805

4

Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline.

Pedersen H, Bräuner-Osborne H, Ball RG, Frydenvang K, Meier E, Bøgesø KP, Krogsgaard-Larsen P. Pedersen H, et al. Among authors: frydenvang k. Bioorg Med Chem. 1999 May;7(5):795-809. doi: 10.1016/s0968-0896(99)00033-4. Bioorg Med Chem. 1999. PMID: 10400332

5

Selective inhibitors of glial GABA uptake: synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and analogues.

Falch E, Perregaard J, FrŁlund B, SŁkilde B, Buur A, Hansen LM, Frydenvang K, Brehm L, Bolvig T, Larsson OM, Sanchez C, White HS, Schousboe A, Krogsgaard-Larsen P. Falch E, et al. Among authors: frydenvang k. J Med Chem. 1999 Dec 30;42(26):5402-14. doi: 10.1021/jm9904452. J Med Chem. 1999. PMID: 10639282

6

GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects.

Krogsgaard-Larsen P, Frølund B, Frydenvang K. Krogsgaard-Larsen P, et al. Among authors: frydenvang k. Curr Pharm Des. 2000 Aug;6(12):1193-209. doi: 10.2174/1381612003399608. Curr Pharm Des. 2000. PMID: 10903390 Review.

7

Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist.

Stensbøl TB, Jensen HS, Nielsen B, Johansen TN, Egebjerg J, Frydenvang K, Krogsgaard-Larsen P. Stensbøl TB, et al. Among authors: frydenvang k. Eur J Pharmacol. 2001 Jan 12;411(3):245-53. doi: 10.1016/s0014-2999(00)00916-x. Eur J Pharmacol. 2001. PMID: 11164381

8

Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors.

Madsen U, Bräuner-Osborne H, Frydenvang K, Hvene L, Johansen TN, Nielsen B, Sánchez C, Stensbøl TB, Bischoff F, Krogsgaard-Larsen P. Madsen U, et al. Among authors: frydenvang k. J Med Chem. 2001 Mar 29;44(7):1051-9. doi: 10.1021/jm000441t. J Med Chem. 2001. PMID: 11297452

9

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA.

Johansen TN, Stensbøl TB, Nielsen B, Vogensen SB, Frydenvang K, Sløk FA, Bräüner-Osborne H, Madsen U, Krogsgaard-Larsen P. Johansen TN, et al. Among authors: frydenvang k. Chirality. 2001;13(9):523-32. doi: 10.1002/chir.1172. Chirality. 2001. PMID: 11579444

10

Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs.

Guldbrandt M, Johansen TN, Frydenvang K, Bräuner-Osborne H, Stensbøl TB, Nielsen B, Karla R, Santi F, Krogsgaard-Larsen P, Madsen U. Guldbrandt M, et al. Among authors: frydenvang k. Chirality. 2002 May 5;14(4):351-63. doi: 10.1002/chir.10104. Chirality. 2002. PMID: 11968078

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