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Page 1
Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.
Aye S, Johansson G, Hock C, Lannfelt L, Sims JR, Blennow K, Frederiksen KS, Graff C, Molinuevo JL, Scheltens P, Palmqvist S, Schöll M, Wimo A, Kivipelto M, Handels R, Frölich L, Zilka N, Tolar M, Johannsen P, Jönsson L, Winblad B. Aye S, et al. Among authors: scheltens p. J Prev Alzheimers Dis. 2025 Jan;12(1):100022. doi: 10.1016/j.tjpad.2024.100022. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800469
evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease.
Cummings JL, Atri A, Feldman HH, Hansson O, Sano M, Knop FK, Johannsen P, León T, Scheltens P. Cummings JL, et al. Among authors: scheltens p. Alzheimers Res Ther. 2025 Jan 8;17(1):14. doi: 10.1186/s13195-024-01666-7. Alzheimers Res Ther. 2025. PMID: 39780249 Free PMC article. Clinical Trial.
X-chromosome-wide association study for Alzheimer's disease.
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S; EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE; Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-… See abstract for full author list ➔ Le Borgne J, et al. Among authors: scheltens p. Mol Psychiatry. 2024 Dec 4. doi: 10.1038/s41380-024-02838-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39633006
Quantification Supports Amyloid PET Visual Assessment of Challenging Cases: Results from the AMYPAD Diagnostic and Patient Management Study.
Collij LE, Bischof GN, Altomare D, Bader I, Battle M, Vállez García D, Lopes Alves I, Wolz R, Gismondi R, Stephens A, Walker Z, Scheltens P, Nordberg A, Gispert JD, Drzezga A, Perissinotti A, Morbelli S, Buckley C, Garibotto V, Frisoni GB, Farrar G, Barkhof F; AMYPAD Consortium. Collij LE, et al. Among authors: scheltens p. J Nucl Med. 2025 Jan 3;66(1):110-116. doi: 10.2967/jnumed.124.268119. J Nucl Med. 2025. PMID: 39542700 Free PMC article.
Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer's disease.
Vermunt L, Sutphen CL, Dicks E, de Leeuw DM, Allegri RF, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Day GS, Ewers M, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Jucker M, Karch CM, Kuhle J, Laske C, Levin J, Masters CL, McDade E, Mori H, Morris JC, Perrin RJ, Preische O, Schofield PR, Suárez-Calvet M, Xiong C, Scheltens P, Teunissen CE, Visser PJ, Bateman RJ, Benzinger TLS, Fagan AM, Gordon BA, Tijms BM. Vermunt L, et al. Among authors: scheltens p. Brain Commun. 2024 Oct 9;6(5):fcae357. doi: 10.1093/braincomms/fcae357. eCollection 2024. Brain Commun. 2024. PMID: 39440304 Free PMC article.
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia.
Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Tijms BM, Verde F, Ticozzi N, Silani V, Visser PJ, Waldman A, Wolz R, Chételat G, Ewers M, Wink AM, Mutsaerts H, Gispert JD, Wardlaw JM, Barkhof F. Lorenzini L, et al. Among authors: scheltens p. Neurology. 2024 Oct 8;103(7):e209801. doi: 10.1212/WNL.0000000000209801. Epub 2024 Sep 17. Neurology. 2024. PMID: 39288341 Free PMC article.
Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Koetsier J, Cavill R, Reijnders R, Harvey J, Homann J, Kouhsar M, Deckers K, Köhler S, Eijssen LMT, van den Hove DLA, Demuth I, Düzel S; Alzheimer's Disease Neuroimaging Initiative; Smith RG, Smith AR, Burrage J, Walker EM, Shireby G, Hannon E, Dempster E, Frayling T, Mill J, Dobricic V, Johannsen P, Wittig M, Franke A, Vandenberghe R, Schaeverbeke J, Freund-Levi Y, Frölich L, Scheltens P, Teunissen CE, Frisoni G, Blin O, Richardson JC, Bordet R, Engelborghs S, de Roeck E, Martinez-Lage P, Tainta M, Lleó A, Sala I, Popp J, Peyratout G, Verhey F, Tsolaki M, Andreasson U, Blennow K, Zetterberg H, Streffer J, Vos SJB, Lovestone S, Visser PJ, Lill CM, Bertram L, Lunnon K, Pishva E. Koetsier J, et al. Among authors: scheltens p. Alzheimers Dement. 2024 Oct;20(10):6682-6698. doi: 10.1002/alz.14061. Epub 2024 Aug 28. Alzheimers Dement. 2024. PMID: 39193899 Free PMC article.
1,271 results