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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E; DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank); EADB (Alzheimer Disease European DNA biobank); IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium); IPDGC (The International Parkinson Disease Genomics Consortium); RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia); Netherlands Brain Bank (NBB); Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kaw… See abstract for full author list ➔ van der Lee SJ, et al. Among authors: skoog i. Acta Neuropathol. 2019 Aug;138(2):237-250. doi: 10.1007/s00401-019-02026-8. Epub 2019 May 27. Acta Neuropathol. 2019. PMID: 31131421 Free PMC article.
Advances in vascular cognitive impairment 2005.
Chui H, Skoog I. Chui H, et al. Among authors: skoog i. Stroke. 2006 Feb;37(2):323-5. doi: 10.1161/01.STR.0000200556.18993.9a. Epub 2006 Jan 12. Stroke. 2006. PMID: 16410472 Review. No abstract available.
Association of complement factor H Y402H gene polymorphism with Alzheimer's disease.
Zetterberg M, Landgren S, Andersson ME, Palmér MS, Gustafson DR, Skoog I, Minthon L, Thelle DS, Wallin A, Bogdanovic N, Andreasen N, Blennow K, Zetterberg H. Zetterberg M, et al. Among authors: skoog i. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):720-6. doi: 10.1002/ajmg.b.30668. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 18163432
Association of the RAGE G82S polymorphism with Alzheimer's disease.
Daborg J, von Otter M, Sjölander A, Nilsson S, Minthon L, Gustafson DR, Skoog I, Blennow K, Zetterberg H. Daborg J, et al. Among authors: skoog i. J Neural Transm (Vienna). 2010 Jul;117(7):861-7. doi: 10.1007/s00702-010-0437-0. Epub 2010 Jun 22. J Neural Transm (Vienna). 2010. PMID: 20567859 Free PMC article.
No association of LOXL1 gene polymorphisms with Alzheimer's disease.
Abramsson A, Landgren S, Zetterberg M, Seibt Palmer M, Minthon L, Gustafson DR, Skoog I, Blennow K, Zetterberg H. Abramsson A, et al. Among authors: skoog i. Neuromolecular Med. 2011 Jun;13(2):160-6. doi: 10.1007/s12017-011-8144-z. Epub 2011 May 11. Neuromolecular Med. 2011. PMID: 21559813
503 results