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The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.
Taylor SE, O'Connor CM, Wang Z, Shen G, Song H, Leonard D, Sangodkar J, LaVasseur C, Avril S, Waggoner S, Zanotti K, Armstrong AJ, Nagel C, Resnick K, Singh S, Jackson MW, Xu W, Haider S, DiFeo A, Narla G. Taylor SE, et al. Among authors: shen g. Cancer Res. 2019 Aug 15;79(16):4242-4257. doi: 10.1158/0008-5472.CAN-19-0218. Epub 2019 May 29. Cancer Res. 2019. PMID: 31142515 Free PMC article.
Structural basis of the Norrin-Frizzled 4 interaction.
Shen G, Ke J, Wang Z, Cheng Z, Gu X, Wei Y, Melcher K, Xu HE, Xu W. Shen G, et al. Cell Res. 2015 Sep;25(9):1078-81. doi: 10.1038/cr.2015.92. Epub 2015 Jul 31. Cell Res. 2015. PMID: 26227961 Free PMC article. No abstract available.
Suppression of epidermal growth factor receptor (EGFR) expression by small hairpin RNA inhibits the growth of human nonsmall cell lung cancers bearing wild-type and mutant EGFR.
Zhang S, Tian H, Jiang Q, Li L, Ding Y, Dai L, Xiang Y, Shen G, Cheng L, Huang Q, Liu Y, Zhang X, Ma Y, Zhang N, Liu S, Wang W, Dai L, Li Y, Zhao X, Wei Y, Deng H. Zhang S, et al. Among authors: shen g. Cancer Invest. 2011 Dec;29(10):701-8. doi: 10.3109/07357907.2011.626480. Cancer Invest. 2011. PMID: 22085274
SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo.
Zhang S, Cao Z, Tian H, Shen G, Ma Y, Xie H, Liu Y, Zhao C, Deng S, Yang Y, Zheng R, Li W, Zhang N, Liu S, Wang W, Dai L, Shi S, Cheng L, Pan Y, Feng S, Zhao X, Deng H, Yang S, Wei Y. Zhang S, et al. Among authors: shen g. Clin Cancer Res. 2011 Jul 1;17(13):4439-50. doi: 10.1158/1078-0432.CCR-10-3109. Epub 2011 May 27. Clin Cancer Res. 2011. PMID: 21622720
Interleukin-37 promotes colitis-associated carcinogenesis via SIGIRR-mediated cytotoxic T cells dysfunction.
Wang Z, Zeng FL, Hu YW, Wang XY, Zhao FL, Zhou P, Hu J, Xiao YY, Hu ZL, Guo MF, Wei XQ, Liu X, Huang NY, Zhang J, Chen SW, Cheng J, Zheng HP, Zhou H, Zhao QX, Zhang C, Hao Y, Zou S, Gui YY, Yu JD, Gu LN, Yue CC, Zhang HZ, Wu WL, Zhou YF, Zhou XK, Shen GB, Teng X, Li J. Wang Z, et al. Signal Transduct Target Ther. 2022 Jan 20;7(1):19. doi: 10.1038/s41392-021-00820-z. Signal Transduct Target Ther. 2022. PMID: 35046386 Free PMC article.
4,838 results