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The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3.
Okalang U, Mualem Bar-Ner B, Rajan KS, Friedman N, Aryal S, Egarmina K, Hope R, Khazanov N, Senderowitz H, Alon A, Fass D, Michaeli S. Okalang U, et al. Among authors: aryal s. mBio. 2021 Dec 21;12(6):e0260221. doi: 10.1128/mBio.02602-21. Epub 2021 Nov 30. mBio. 2021. PMID: 34844425 Free PMC article.
A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Rajan KS, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe Y, Doniger T, Galili Kostin B, Blumberg A, Cohen-Chalamish S, Schwartz S, Rivalta A, Zimmerman E, Unger R, Isobe T, Yonath A, Michaeli S. Rajan KS, et al. Among authors: aryal s. Nat Commun. 2023 Nov 20;14(1):7462. doi: 10.1038/s41467-023-43263-6. Nat Commun. 2023. PMID: 37985661 Free PMC article.
Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Späth GF, Yonath A, Michaeli S. Rajan KS, et al. Among authors: aryal s. Cell Rep. 2024 May 28;43(5):114203. doi: 10.1016/j.celrep.2024.114203. Epub 2024 May 8. Cell Rep. 2024. PMID: 38722744 Free PMC article.
The ketone body β-Hydroxybutyrate mediated epigenetic chromatin β-hydroxybutyrylation protects kidneys.
Mandal J, Aryal S, Manandhar I, Chakraborty S, Mei X, Yeoh BS, Mell B, Kleinhenz A, Tummala R, Yang T, Saha P, Gunning WT, Vijay-Kumar M, Basrur V, de la Serna I, Joe B. Mandal J, et al. Among authors: aryal s. bioRxiv [Preprint]. 2024 Dec 21:2024.12.18.628574. doi: 10.1101/2024.12.18.628574. bioRxiv. 2024. PMID: 39763881 Free PMC article. Preprint.
511 results