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Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation.
Ramírez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C. Ramírez CM, et al. Among authors: lee wl. Circulation. 2019 Jul 16;140(3):225-239. doi: 10.1161/CIRCULATIONAHA.118.038571. Epub 2019 Jun 3. Circulation. 2019. PMID: 31154825 Free PMC article.
The Tie2-agonist Vasculotide rescues mice from influenza virus infection.
Sugiyama MG, Armstrong SM, Wang C, Hwang D, Leong-Poi H, Advani A, Advani S, Zhang H, Szaszi K, Tabuchi A, Kuebler WM, Van Slyke P, Dumont DJ, Lee WL. Sugiyama MG, et al. Among authors: lee wl. Sci Rep. 2015 Jun 5;5:11030. doi: 10.1038/srep11030. Sci Rep. 2015. PMID: 26046800 Free PMC article.
A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.
Armstrong SM, Sugiyama MG, Fung KY, Gao Y, Wang C, Levy AS, Azizi P, Roufaiel M, Zhu SN, Neculai D, Yin C, Bolz SS, Seidah NG, Cybulsky MI, Heit B, Lee WL. Armstrong SM, et al. Among authors: lee wl. Cardiovasc Res. 2015 Nov 1;108(2):268-77. doi: 10.1093/cvr/cvv218. Epub 2015 Sep 2. Cardiovasc Res. 2015. PMID: 26334034 Free PMC article.
Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.
Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC. Kraehling JR, et al. Among authors: lee wl, lee my. Nat Commun. 2016 Nov 21;7:13516. doi: 10.1038/ncomms13516. Nat Commun. 2016. PMID: 27869117 Free PMC article.
Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2-SR-BI Axis.
Ghaffari S, Jang E, Naderinabi F, Sanwal R, Khosraviani N, Wang C, Steinberg BE, Goldenberg NM, Ikeda J, Lee WL. Ghaffari S, et al. Among authors: lee wl. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):200-216. doi: 10.1161/ATVBAHA.120.314557. Epub 2020 Oct 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33054399 Free article.
Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation.
Ikeda J, Scipione CA, Hyduk SJ, Althagafi MG, Atif J, Dick SA, Rajora M, Jang E, Emoto T, Murakami J, Ikeda N, Ibrahim HM, Polenz CK, Gao X, Tai K, Jongstra-Bilen J, Nakashima R, Epelman S, Robbins CS, Zheng G, Lee WL, MacParland SA, Cybulsky MI. Ikeda J, et al. Among authors: lee wl. Circ Res. 2021 Feb 19;128(4):530-543. doi: 10.1161/CIRCRESAHA.119.316539. Epub 2021 Jan 5. Circ Res. 2021. PMID: 33397122
917 results