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Modeling linear and cyclic PKS intermediates through atom replacement.
Shakya G, Rivera H Jr, Lee DJ, Jaremko MJ, La Clair JJ, Fox DT, Haushalter RW, Schaub AJ, Bruegger J, Barajas JF, White AR, Kaur P, Gwozdziowski ER, Wong F, Tsai SC, Burkart MD. Shakya G, et al. Among authors: tsai sc. J Am Chem Soc. 2014 Dec 3;136(48):16792-9. doi: 10.1021/ja5064857. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25406716 Free PMC article.
Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases.
Barajas JF, Shakya G, Moreno G, Rivera H Jr, Jackson DR, Topper CL, Vagstad AL, La Clair JJ, Townsend CA, Burkart MD, Tsai SC. Barajas JF, et al. Among authors: tsai sc. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4142-E4148. doi: 10.1073/pnas.1609001114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484029 Free PMC article.
723 results