Kohn DB - Search Results

1

Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates.

Romero Z, Lomova A, Said S, Miggelbrink A, Kuo CY, Campo-Fernandez B, Hoban MD, Masiuk KE, Clark DN, Long J, Sanchez JM, Velez M, Miyahira E, Zhang R, Brown D, Wang X, Kurmangaliyev YZ, Hollis RP, Kohn DB. Romero Z, et al. Among authors: kohn db. Mol Ther. 2019 Aug 7;27(8):1389-1406. doi: 10.1016/j.ymthe.2019.05.014. Epub 2019 May 24. Mol Ther. 2019. PMID: 31178391 Free PMC article.

2

Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells.

Nolta JA, Kohn DB. Nolta JA, et al. Among authors: kohn db. Hum Gene Ther. 1990 Fall;1(3):257-68. doi: 10.1089/hum.1990.1.3-257. Hum Gene Ther. 1990. PMID: 2081193

3

Expression of biologically active human factor IX in human hematopoietic cells after retroviral vector-mediated gene transduction.

Hao QL, Malik P, Salazar R, Tang H, Gordon EM, Kohn DB. Hao QL, et al. Among authors: kohn db. Hum Gene Ther. 1995 Jul;6(7):873-80. doi: 10.1089/hum.1995.6.7-873. Hum Gene Ther. 1995. PMID: 7578406

4

The current status of gene therapy using hematopoietic stem cells.

Kohn DB. Kohn DB. Curr Opin Pediatr. 1995 Feb;7(1):56-63. doi: 10.1097/00008480-199502000-00011. Curr Opin Pediatr. 1995. PMID: 7728204 Review.

5

The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long-term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease.

Wells S, Malik P, Pensiero M, Kohn DB, Nolta JA. Wells S, et al. Among authors: kohn db. Gene Ther. 1995 Oct;2(8):512-20. Gene Ther. 1995. PMID: 8593601

6

Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice.

Nolta JA, Dao MA, Wells S, Smogorzewska EM, Kohn DB. Nolta JA, et al. Among authors: kohn db. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2414-9. doi: 10.1073/pnas.93.6.2414. Proc Natl Acad Sci U S A. 1996. PMID: 8637888 Free PMC article.

7

Increased levels of spliced RNA account for augmented expression from the MFG retroviral vector in hematopoietic cells.

Krall WJ, Skelton DC, Yu XJ, Riviere I, Lehn P, Mulligan RC, Kohn DB. Krall WJ, et al. Among authors: kohn db. Gene Ther. 1996 Jan;3(1):37-48. Gene Ther. 1996. PMID: 8929910

8

Retrovirus-mediated transfer of the human alpha-L-iduronidase cDNA into human hematopoietic progenitor cells leads to correction in trans of Hurler fibroblasts.

Huang MM, Wong A, Yu X, Kakkis E, Kohn DB. Huang MM, et al. Among authors: kohn db. Gene Ther. 1997 Nov;4(11):1150-9. doi: 10.1038/sj.gt.3300504. Gene Ther. 1997. PMID: 9425437

9

Stem cell directed gene therapy.

Engel BC, Kohn DB. Engel BC, et al. Among authors: kohn db. Front Biosci. 1999 May 1;4:e26-33. doi: 10.2741/engel. Front Biosci. 1999. PMID: 10228093 Review.

10

Expression of human Wiskott-Aldrich syndrome protein in patients' cells leads to partial correction of a phenotypic abnormality of cell surface glycoproteins.

Huang MM, Tsuboi S, Wong A, Yu XJ, Oh-Eda M, Derry JM, Francke U, Fukuda M, Weinberg KI, Kohn DB. Huang MM, et al. Among authors: kohn db. Gene Ther. 2000 Feb;7(4):314-20. doi: 10.1038/sj.gt.3301085. Gene Ther. 2000. PMID: 10694812

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