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Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA.
Dorin-Semblat D, Tétard M, Claës A, Semblat JP, Dechavanne S, Fourati Z, Hamelin R, Armand F, Matesic G, Nunes-Silva S, Srivastava A, Gangnard S, Lopez-Rubio JJ, Moniatte M, Doerig C, Scherf A, Gamain B. Dorin-Semblat D, et al. Among authors: srivastava a. PLoS Biol. 2019 Jun 10;17(6):e3000308. doi: 10.1371/journal.pbio.3000308. eCollection 2019 Jun. PLoS Biol. 2019. PMID: 31181082 Free PMC article.
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA.
Srivastava A, Gangnard S, Round A, Dechavanne S, Juillerat A, Raynal B, Faure G, Baron B, Ramboarina S, Singh SK, Belrhali H, England P, Lewit-Bentley A, Scherf A, Bentley GA, Gamain B. Srivastava A, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4884-9. doi: 10.1073/pnas.1000951107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194779 Free PMC article.
Parity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria.
Dechavanne S, Srivastava A, Gangnard S, Nunes-Silva S, Dechavanne C, Fievet N, Deloron P, Chêne A, Gamain B. Dechavanne S, et al. Among authors: srivastava a. Infect Immun. 2015 Jun;83(6):2466-74. doi: 10.1128/IAI.03116-14. Epub 2015 Mar 30. Infect Immun. 2015. PMID: 25824842 Free PMC article.
Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy.
de Moraes LV, Dechavanne S, Sousa PM, Barateiro A, Cunha SF, Nunes-Silva S, Lima FA, Murillo O, Marinho CRF, Gangnard S, Srivastava A, Braks JA, Janse CJ, Gamain B, Franke-Fayard B, Penha-Gonçalves C. de Moraes LV, et al. Among authors: srivastava a. Infect Immun. 2016 May 24;84(6):1761-1774. doi: 10.1128/IAI.01207-15. Print 2016 Jun. Infect Immun. 2016. PMID: 27045035 Free PMC article.
Correction for de Moraes et al., "Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy".
de Moraes LV, Dechavanne S, Sousa PM, Barateiro A, Cunha SF, Nunes-Silva S, Lima FA, Murillo O, Marinho CRF, Gangnard S, Srivastava A, Braks JA, Janse CJ, Gamain B, Franke-Fayard B, Penha-Gonçalves C. de Moraes LV, et al. Among authors: srivastava a. Infect Immun. 2017 Nov 17;85(12):e00590-17. doi: 10.1128/IAI.00590-17. Print 2017 Dec. Infect Immun. 2017. PMID: 29150483 Free PMC article. No abstract available.
7,393 results