Hoffbrand AV - Search Results

1

Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.

Kontoghiorghes GJ, Aldouri MA, Hoffbrand AV, Barr J, Wonke B, Kourouclaris T, Sheppard L. Kontoghiorghes GJ, et al. Among authors: hoffbrand av. Br Med J (Clin Res Ed). 1987 Dec 12;295(6612):1509-12. doi: 10.1136/bmj.295.6612.1509. Br Med J (Clin Res Ed). 1987. PMID: 3122880 Free PMC article. Clinical Trial.

2

High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: reversal by intensified chelation.

Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Ward SE, Agnew JE, Hilson AJ. Aldouri MA, et al. Among authors: hoffbrand av. Acta Haematol. 1990;84(3):113-7. doi: 10.1159/000205046. Acta Haematol. 1990. PMID: 2123060

3

Cardiac complications in homozygous beta-thalassemia.

Wonke B, Hoffbrand AV, Aldouri MA, Ward SE. Wonke B, et al. Among authors: hoffbrand av. Prog Clin Biol Res. 1989;309:51-6. Prog Clin Biol Res. 1989. PMID: 2780750 No abstract available.

4

1,2-Dimethyl-3-hydroxypyrid-4-one, an orally active chelator for treatment of iron overload.

Kontoghiorghes GJ, Aldouri MA, Sheppard L, Hoffbrand AV. Kontoghiorghes GJ, et al. Among authors: hoffbrand av. Lancet. 1987 Jun 6;1(8545):1294-5. doi: 10.1016/s0140-6736(87)90545-9. Lancet. 1987. PMID: 2884415

5

Iron state and hepatic disease in patients with thalassaemia major, treated with long term subcutaneous desferrioxamine.

Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Laulicht M, Fenton LA, Scheuer PJ, Kibbler CC, Allwood CA, Brown D, et al. Aldouri MA, et al. Among authors: hoffbrand av. J Clin Pathol. 1987 Nov;40(11):1353-9. doi: 10.1136/jcp.40.11.1353. J Clin Pathol. 1987. PMID: 3121679 Free PMC article.

6

The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.

Jeremy JY, Kontoghiorghes GJ, Hoffbrand AV, Dandona P. Jeremy JY, et al. Among authors: hoffbrand av. Biochem J. 1988 Aug 15;254(1):239-44. doi: 10.1042/bj2540239. Biochem J. 1988. PMID: 3140797 Free PMC article.

7

Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats.

Kontoghiorghes GJ, Sheppard L, Hoffbrand AV, Charalambous J, Tikerpae J, Pippard MJ. Kontoghiorghes GJ, et al. Among authors: hoffbrand av. J Clin Pathol. 1987 Apr;40(4):404-8. doi: 10.1136/jcp.40.4.404. J Clin Pathol. 1987. PMID: 3584483 Free PMC article.

8

Results of long-term deferiprone (L1) therapy: a report by the International Study Group on Oral Iron Chelators.

al-Refaie FN, Hershko C, Hoffbrand AV, Kosaryan M, Olivieri NF, Tondury P, Wonke B. al-Refaie FN, et al. Among authors: hoffbrand av. Br J Haematol. 1995 Sep;91(1):224-9. doi: 10.1111/j.1365-2141.1995.tb05274.x. Br J Haematol. 1995. PMID: 7577638

9

Changes in transferrin saturation after treatment with the oral iron chelator deferiprone in patients with iron overload.

al-Refaie FN, De Silva CE, Wonke B, Hoffbrand AV. al-Refaie FN, et al. Among authors: hoffbrand av. J Clin Pathol. 1995 Feb;48(2):110-4. doi: 10.1136/jcp.48.2.110. J Clin Pathol. 1995. PMID: 7745107 Free PMC article.

10

Deferiprone-associated myelotoxicity.

al-Refaie FN, Wonke B, Hoffbrand AV. al-Refaie FN, et al. Among authors: hoffbrand av. Eur J Haematol. 1994 Nov;53(5):298-301. doi: 10.1111/j.1600-0609.1994.tb01323.x. Eur J Haematol. 1994. PMID: 7813710 Clinical Trial.

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