Velagapudi SP - Search Results

1

Identifying and validating small molecules interacting with RNA (SMIRNAs).

Disney MD, Velagapudi SP, Li Y, Costales MG, Childs-Disney JL. Disney MD, et al. Among authors: velagapudi sp. Methods Enzymol. 2019;623:45-66. doi: 10.1016/bs.mie.2019.04.027. Epub 2019 May 15. Methods Enzymol. 2019. PMID: 31239057 Free PMC article.

2

Defining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing.

Velagapudi SP, Disney MD. Velagapudi SP, et al. Bioorg Med Chem. 2013 Oct 15;21(20):6132-8. doi: 10.1016/j.bmc.2013.04.072. Epub 2013 May 7. Bioorg Med Chem. 2013. PMID: 23719281 Free PMC article.

3

Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor.

Velagapudi SP, Disney MD. Velagapudi SP, et al. Chem Commun (Camb). 2014 Mar 21;50(23):3027-9. doi: 10.1039/c3cc00173c. Chem Commun (Camb). 2014. PMID: 24503738 Free PMC article.

4

Sequence-based design of bioactive small molecules that target precursor microRNAs.

Velagapudi SP, Gallo SM, Disney MD. Velagapudi SP, et al. Nat Chem Biol. 2014 Apr;10(4):291-7. doi: 10.1038/nchembio.1452. Epub 2014 Feb 9. Nat Chem Biol. 2014. PMID: 24509821 Free PMC article.

5

Small molecule chemical probes of microRNA function.

Velagapudi SP, Vummidi BR, Disney MD. Velagapudi SP, et al. Curr Opin Chem Biol. 2015 Feb;24:97-103. doi: 10.1016/j.cbpa.2014.10.024. Epub 2014 Dec 10. Curr Opin Chem Biol. 2015. PMID: 25500006 Free PMC article. Review.

6

Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNA.

Yang WY, Wilson HD, Velagapudi SP, Disney MD. Yang WY, et al. Among authors: velagapudi sp. J Am Chem Soc. 2015 Apr 29;137(16):5336-45. doi: 10.1021/ja507448y. Epub 2015 Apr 15. J Am Chem Soc. 2015. PMID: 25825793 Free PMC article.

7

Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs.

Disney MD, Winkelsas AM, Velagapudi SP, Southern M, Fallahi M, Childs-Disney JL. Disney MD, et al. Among authors: velagapudi sp. ACS Chem Biol. 2016 Jun 17;11(6):1720-8. doi: 10.1021/acschembio.6b00001. Epub 2016 Apr 20. ACS Chem Biol. 2016. PMID: 27097021 Free PMC article.

8

Design of a small molecule against an oncogenic noncoding RNA.

Velagapudi SP, Cameron MD, Haga CL, Rosenberg LH, Lafitte M, Duckett DR, Phinney DG, Disney MD. Velagapudi SP, et al. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903. doi: 10.1073/pnas.1523975113. Epub 2016 May 11. Proc Natl Acad Sci U S A. 2016. PMID: 27170187 Free PMC article.

9

Rapid Generation of miRNA Inhibitor Leads by Bioinformatics and Efficient High-Throughput Screening Methods.

Haga CL, Velagapudi SP, Childs-Disney JL, Strivelli J, Disney MD, Phinney DG. Haga CL, et al. Among authors: velagapudi sp. Methods Mol Biol. 2017;1517:179-198. doi: 10.1007/978-1-4939-6563-2_13. Methods Mol Biol. 2017. PMID: 27924483

10

Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit.

Costales MG, Haga CL, Velagapudi SP, Childs-Disney JL, Phinney DG, Disney MD. Costales MG, et al. Among authors: velagapudi sp. J Am Chem Soc. 2017 Mar 8;139(9):3446-3455. doi: 10.1021/jacs.6b11273. Epub 2017 Feb 27. J Am Chem Soc. 2017. PMID: 28240549 Free PMC article.

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