Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases.
Griffiths JS, Thompson A, Stott M, Benny A, Lewis NA, Taylor PR, Forton J, Herrick S, Orr SJ, McGreal EP.
Griffiths JS, et al. Among authors: thompson a.
FASEB J. 2018 Jun;32(6):3385-3397. doi: 10.1096/fj.201701145R. Epub 2018 Jan 22.
FASEB J. 2018.
PMID: 29401615
Free PMC article.
Thus, Dectin-1 and Dectin-2 cleavage by NE and/or A. fumigatus-derived proteases results in an aberrant antifungal immune response that likely contributes to disease pathology in patients with CF.-Griffiths, J. S., Thompson, A., Stott, M., Benny, A., L …
Thus, Dectin-1 and Dectin-2 cleavage by NE and/or A. fumigatus-derived proteases results in an aberrant antifungal immune response th …